KEGG   DRUG: D03011Help
Entry
D03011                      Drug                                   

Name
Atropine oxide hydrochloride (USAN);
Genatropine hydrochloride
Formula
C17H23NO4. HCl
Exact mass
341.1394
Mol weight
341.8298
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic
Remark
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03B BELLADONNA AND DERIVATIVES, PLAIN
    A03BA Belladonna alkaloids, tertiary amines
     A03BA01 Atropine
      D03011  Atropine oxide hydrochloride (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA01 Atropine
      D03011  Atropine oxide hydrochloride (USAN)
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Atropine
    D03011  Atropine oxide hydrochloride (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Atropine
      D03011  Atropine oxide hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
4574-60-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   X   Cl   32.2700  -19.6000
            2   C1x C    19.2038  -19.7208
            3   C1x C    19.5319  -18.5491
            4   C1y C    20.3755  -19.4396
            5   C1y C    20.7036  -18.2679
            6   N2y N    19.4382  -16.9556
            7   C1x C    22.2502  -19.4396
            8   C1x C    21.9690  -18.2679
            9   C1y C    23.2813  -20.0020
            10  O7a O    24.3593  -20.8925
            11  C7a C    25.5779  -20.8925
            12  C1c C    26.1872  -19.8145
            13  O6a O    26.1872  -22.0173
            14  C8y C    27.4058  -19.8145
            15  C1b C    25.5779  -18.7834
            16  O1a O    26.1872  -17.7055
            17  C8x C    28.1120  -21.0382
            18  C8x C    29.5120  -21.0385
            19  C8x C    30.2122  -19.8262
            20  C8x C    29.5061  -18.6025
            21  C8x C    28.1061  -18.6022
            22  C1a C    18.6891  -15.7714
            23  O3a O    18.2089  -17.5683
BOND        24
            1     2   3 1
            2     2   4 1
            3     3   5 1
            4     4   6 1
            5     4   7 1
            6     5   8 1
            7     7   9 1
            8     9  10 1 #Down
            9    10  11 1
            10   11  12 1
            11   11  13 2
            12   12  14 1
            13   12  15 1
            14   15  16 1
            15    5   6 1
            16    8   9 1
            17   14  17 2
            18   17  18 1
            19   18  19 2
            20   19  20 1
            21   20  21 2
            22   14  21 1
            23    6  22 1
            24    6  23 2

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