KEGG   DRUG: D03046Help
Entry
D03046                      Drug                                   

Name
Cytarabine ocfosphate hydrate (JAN);
Fosteabine sodium monohydrate;
Starasid (TN)
Formula
C27H49N3O8P. Na. H2O
Exact mass
615.3261
Mol weight
615.6721
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antineoplastic [DS:H00003]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Arabinofuranosyl derivative
prodrug, active substance: Cytarabine [DR:D00168]
Target
DNA polymerase inhibitor [EC:2.7.7.7]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01B ANTIMETABOLITES
    L01BC Pyrimidine analogues
     L01BC01 Cytarabine
      D03046  Cytarabine ocfosphate hydrate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   422  Antimetabolites
    4224  Cytosines
     D03046  Cytarabine ocfosphate hydrate (JAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Transferases
   DNA polymerase
    Cytarabine
     D03046  Cytarabine ocfosphate hydrate (JAN)
Antineoplastics [BR:br08308]
 Antimetabolites
  Pyrimidine analogs
   Cytarabine
    D03046  Cytarabine ocfosphate hydrate (JAN)
BRITE hierarchy
Other DBs
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        41
            1   C1y C    35.8364  -16.8675
            2   N4y N    37.1806  -16.3426
            3   O2x O    34.7127  -16.0505
            4   C1y C    35.4078  -18.1826
            5   C1y C    33.5886  -16.8675
            6   C1y C    34.0174  -18.1826
            7   O1a O    36.2188  -19.3066
            8   C8x C    37.1747  -14.9563
            9   C8y C    38.3840  -17.0306
            10  N5x N    39.5817  -16.3325
            11  C8y C    39.5759  -14.9463
            12  C8x C    38.3723  -14.2582
            13  O5x O    38.3894  -18.3954
            14  N1a N    40.7996  -14.2332
            15  C1b C    32.3873  -16.1739
            16  O2b O    31.1859  -16.8675
            17  O1a O    33.2246  -19.2756
            18  P1b P    29.9900  -16.1769
            19  O2b O    28.7773  -16.8773
            20  C1b C    27.2158  -16.1767
            21  O1c O    30.9709  -15.1959 #-
            22  O1c O    29.0092  -15.1959
            23  C1b C    26.0032  -16.8779
            24  C1b C    24.7877  -16.1775
            25  C1b C    23.5763  -16.8790
            26  C1b C    22.3796  -16.1704
            27  C1b C    21.1670  -16.8705
            28  C1b C    19.9544  -16.1704
            29  C1b C    18.7419  -16.8705
            30  C1b C    17.5293  -16.1704
            31  C1b C    16.3167  -16.8705
            32  C1b C    15.1042  -16.1704
            33  C1b C    13.8916  -16.8705
            34  C1b C    12.6790  -16.1704
            35  C1b C    11.4664  -16.8705
            36  C1b C    10.2538  -16.1704
            37  C1b C     9.0413  -16.8705
            38  C1b C     7.8287  -16.1704
            39  C1a C     6.6161  -16.8705
            40  Z   Na   32.5245  -14.7624 #+
            41  O0  O    41.6843  -17.6750
BOND        40
            1     1   2 1 #Up
            2     1   3 1
            3     1   4 1
            4     3   5 1
            5     4   6 1
            6     4   7 1 #Up
            7     5   6 1
            8     2   8 1
            9     2   9 1
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13    8  12 2
            14    9  13 2
            15   11  14 1
            16    5  15 1 #Up
            17   15  16 1
            18    6  17 1 #Down
            19   16  18 1
            20   18  19 1
            21   18  21 1
            22   18  22 2
            23   24  25 1
            24   19  20 1
            25   20  23 1
            26   23  24 1
            27   25  26 1
            28   26  27 1
            29   27  28 1
            30   28  29 1
            31   29  30 1
            32   30  31 1
            33   31  32 1
            34   32  33 1
            35   33  34 1
            36   34  35 1
            37   35  36 1
            38   36  37 1
            39   37  38 1
            40   38  39 1

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