KEGG   DRUG: D03068Help
Entry
D03068                      Drug                                   

Name
Belimumab (genetical recombination) (JAN);
Belimumab (USAN);
Benlysta (TN);
LymphoStat-B (TN)
Product
Formula
C6714H10428N1816O2102S52
Exact mass
151791.04
Mol weight
151884.9241
Activity
Treatment of autoimmune disease [DS:H00080]
Remark
ATC code: 
Comment
human IgG1 monoclonal antibody
Target
BAFF [HSA:10673] [KO:K05476]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa05323  Rheumatoid arthritis  
 
Interaction
Genomic biomarker: TNFSF13B [HSA:10673]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AA Selective immunosuppressants
     L04AA26 Belimumab
      D03068  Belimumab (genetical recombination) (JAN); Belimumab (USAN)
USP drug classification [BR:br08302]
 Immunological Agents
  Immunomodulators
   Belimumab
    D03068  Belimumab (genetical recombination) (JAN); Belimumab (USAN)
Target-based classification of drugs [BR:br08310]
 Cytokines
  TNF family
   BAFF
    Belimumab
     D03068  Belimumab (genetical recombination) (JAN); Belimumab (USAN)
BRITE hierarchy
Other DBs
CAS: 
356547-88-1
PubChem: 
NIKKAJI: 

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