| Entry |
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| Name |
Bexarotene (USAN/INN);
Targretin (TN)
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| Product |
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| Formula |
C24H28O2
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| Exact mass |
348.2089
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| Mol weight |
348.4779
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| Structure |
     |
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| Activity |
Antineoplastic used in the treatment of cutaneous T-cell lymphoma;
Antidiabetic
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| Remark |
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| Comment |
Indication: Cutaneous T-cell lymphoma
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
| Retinoic acid receptor (RAR) and retinoid X receptor (RXR) agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01X OTHER ANTINEOPLASTIC AGENTS
L01XX Other antineoplastic agents
L01XX25 Bexarotene
D03106 Bexarotene (USAN/INN)
USP drug classification [BR:br08302]
Antineoplastics
Retinoids
Bexarotene
D03106 Bexarotene (USAN/INN)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Hepatocyte nuclear factor 4 like receptors
Retinoid X receptor (RXR)
retinoid receptor [HSA:6256 6257 6258] [KO:K08524 K08525 K06258]
Bexarotene [ATC:L01XX25]
D03106 Bexarotene (USAN/INN)
Antineoplastics [BR:br08308]
Miscellaneous agents
Other antineoplastic agents
Bexarotene [ATC:L01XX25]
D03106 Bexarotene (USAN/INN)
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| Other DBs |
CAS: 153559-49-0 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 26
1 C8y C 20.5100 -21.2100
2 C8y C 20.5100 -22.6100
3 C1z C 19.3200 -23.3100
4 C1x C 18.1300 -22.6100
5 C1x C 18.1300 -21.2100
6 C1z C 19.3200 -20.5100
7 C8x C 21.7700 -20.5100
8 C8y C 22.9600 -21.2100
9 C8y C 22.9600 -22.6100
10 C8x C 21.7700 -23.3100
11 C2c C 24.1500 -20.5100
12 C8y C 25.4100 -21.2100
13 C1a C 18.3400 -19.5300
14 C1a C 20.3000 -19.5300
15 C1a C 20.3700 -24.2900
16 C1a C 18.3400 -24.2900
17 C2a C 24.1500 -19.1100
18 C1a C 24.1500 -23.3100
19 C8x C 26.6000 -20.5100
20 C8x C 27.7900 -21.2100
21 C8y C 27.7900 -22.6100
22 C8x C 26.6000 -23.3100
23 C8x C 25.4100 -22.6100
24 C6a C 28.9800 -23.3100
25 O6a O 30.2400 -22.5400
26 O6a O 28.9800 -24.6400
BOND 28
1 11 12 1
2 1 7 1
3 7 8 2
4 8 9 1
5 9 10 2
6 10 2 1
7 5 6 1
8 6 1 1
9 1 2 2
10 6 13 1
11 2 3 1
12 6 14 1
13 3 4 1
14 3 15 1
15 4 5 1
16 3 16 1
17 8 11 1
18 11 17 2
19 9 18 1
20 12 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 12 23 1
26 21 24 1
27 24 25 1
28 24 26 2
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