KEGG   DRUG: D03177Help
Entry
D03177                      Drug                                   

Name
Bunolol hydrochloride (USAN)
Formula
C17H25NO3. HCl
Exact mass
327.1601
Mol weight
327.8462
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-adrenergic [beta-receptor]
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Bunolol
      D03177  Bunolol hydrochloride (USAN)
    beta2-adrenergic receptor
     Bunolol
      D03177  Bunolol hydrochloride (USAN)
    beta3-adrenergic receptor
     Bunolol
      D03177  Bunolol hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
31969-05-8
PubChem: 
LigandBox: 
KCF data Show

ATOM        22
            1   C8y C    15.5176  -12.4873
            2   C8y C    14.3203  -11.7830
            3   C8y C    16.7853  -11.7830
            4   C1x C    15.5176  -13.8960
            5   C5x C    13.1229  -12.4873
            6   C8x C    14.3203  -10.3744
            7   C8x C    16.7853  -10.3744
            8   O2a O    17.9827  -12.4873
            9   C1x C    14.3203  -14.6003
            10  C1x C    13.1229  -13.8960
            11  C8x C    15.5176   -9.6701
            12  C1b C    19.1800  -11.7830
            13  C1c C    20.4477  -12.4873
            14  C1b C    21.6451  -11.7830
            15  O1a O    20.4477  -13.8960
            16  N1b N    22.8424  -12.4873
            17  C1d C    24.1101  -11.7830
            18  C1a C    25.3075  -12.4873
            19  C1a C    24.1101  -10.5857
            20  C1a C    25.3300  -11.0787
            21  O5x O    11.8710  -11.7715
            22  X   Cl   30.1700  -13.8600
BOND        22
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    6  11 2
            11    8  12 1
            12   12  13 1
            13   13  14 1
            14   13  15 1
            15   14  16 1
            16   16  17 1
            17   17  18 1
            18   17  19 1
            19    7  11 1
            20    9  10 1
            21   17  20 1
            22    5  21 2

» Japanese version   » Back

DBGET integrated database retrieval system