KEGG   DRUG: Butoxamine hydrochlorideHelp
Entry
D03198                      Drug                                   

Name
Butoxamine hydrochloride (USAN)
Formula
C15H25NO3. HCl
Exact mass
303.1601
Mol weight
303.8248
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
Activity
Antidiabetic, Antidyslipidemia (hyperlipoproteinemic)
Target
ADRB2 [HSA:154] [KO:K04142]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor
     Butoxamine
      D03198  Butoxamine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
5696-15-1
PubChem: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   C8x C    17.2123  -18.4361
            2   C8y C    17.2123  -19.8362
            3   C8x C    18.4278  -20.5363
            4   C8x C    19.6362  -19.8362
            5   C8y C    19.6362  -18.4361
            6   C8y C    18.4278  -17.7360
            7   O2a O    16.0000  -20.5370
            8   C1a C    14.7873  -19.8376
            9   O2a O    20.8493  -17.7370
            10  C1a C    22.0612  -18.4379
            11  C1c C    18.4295  -16.3359
            12  C1c C    19.6429  -15.6373
            13  N1b N    20.8547  -16.3389
            14  C1d C    22.0681  -15.6404
            15  C1a C    23.2797  -16.3420
            16  C1a C    22.0698  -14.2403
            17  O1a O    17.2179  -15.6343
            18  C1a C    19.6442  -14.2102
            19  C1a C    23.2805  -14.9404
            20  X   Cl   27.6850  -17.8704
BOND        19
            1     5   9 1
            2     2   3 1
            3     9  10 1
            4     3   4 2
            5     6  11 1
            6     4   5 1
            7    11  12 1
            8     5   6 2
            9    12  13 1
            10    6   1 1
            11   13  14 1
            12   14  15 1
            13    2   7 1
            14   14  16 1
            15   11  17 1
            16    7   8 1
            17    1   2 2
            18   12  18 1
            19   14  19 1

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