KEGG   DRUG: Epoetin alfaHelp
Entry
D03231                      Drug                                   

Name
Epoetin alfa (USAN/INN);
Epoetin alfa (genetical recombination) (JP17);
Epogen (TN)
Product
Formula
C809H1301N229O240S5
Exact mass
18224.5242
Mol weight
18235.7015
Sequence
APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA
VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS
PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGD
(Disulfide bridge: 7-161; 29-33)
  Type
Peptide
Remark
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Anti-anemic, Hematinic, Erythropoietin receptor agonist
Target
EPOR [HSA:2057] [KO:K05079]
  Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Hematopoietic cell lineage
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B03 ANTIANEMIC PREPARATIONS
   B03X OTHER ANTIANEMIC PREPARATIONS
    B03XA Other antianemic preparations
     B03XA01 Erythropoietin
      D03231  Epoetin alfa (USAN/INN)
USP drug classification [BR:br08302]
 Blood Products/Modifiers/Volume Expanders
  Blood Formation Modifiers
   Epoetin alfa
    D03231  Epoetin alfa (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D03231  Epoetin alfa (USAN/INN); Epoetin alfa (genetical recombination) (JP17)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class I cytokine receptors (hematopoietin family receptors)
   erythropoietin receptor
    Erythropoietin
     D03231  Epoetin alfa (USAN/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D03231  Epoetin alfa (genetical recombination)
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D03231
BRITE hierarchy
Other DBs
CAS: 
113427-24-0
PubChem: 
DrugBank: 

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