KEGG   DRUG: D03231Help
Entry
D03231                      Drug                                   

Name
Epoetin alfa (genetical recombination) (JP16);
Epoetin alfa (USAN/INN);
Epogen (TN)
Product
Formula
C809H1301N229O240S5
Exact mass
18224.5242
Mol weight
18235.7015
Sequence
APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA
VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS
PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGD
(Disulfide bridge: 7-161; 29-33)
  Type
Peptide
Activity
Anti-anemic;
Hematinic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
erythropoietin receptor agonist [HSA:2057] [KO:K05079]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  Jak-STAT signaling pathway
hsa04640  Hematopoietic cell lineage  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B03 ANTIANEMIC PREPARATIONS
   B03X OTHER ANTIANEMIC PREPARATIONS
    B03XA Other antianemic preparations
     B03XA01 Erythropoietin
      D03231  Epoetin alfa (genetical recombination) (JAN); Epoetin alfa (USAN/INN)
USP drug classification [BR:br08302]
 Blood Products/Modifiers/Volume Expanders
  Blood Formation Modifiers
   Epoetin alfa
    D03231  Epoetin alfa (genetical recombination) (JAN); Epoetin alfa (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D03231  Epoetin alfa (genetical recombination) (JP16); Epoetin alfa (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class I cytokine receptors (hematopoietin family receptors)
   erythropoietin receptor
    Erythropoietin
     D03231  Epoetin alfa (genetical recombination) (JAN); Epoetin alfa (USAN/INN)
Antineoplastics [BR:br08308]
 Biologic response modifiers
  Myeloid- and erythroid-stimulating factors
   Erythropoietin
    D03231  Epoetin alfa (genetical recombination) (JAN); Epoetin alfa (USAN/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D03231  Epoetin alfa (genetical recombination)
BRITE hierarchy
Other DBs
CAS: 
113427-24-0
PubChem: 
DrugBank: 

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