KEGG   DRUG: Mazaticol hydrochloride hydrateHelp
Entry
D03264                      Drug                                   

Name
Mazaticol hydrochloride hydrate (JAN);
Mazaticol hydrochloride;
Pentona (TN)
Formula
C21H27NO3S2. HCl. H2O
Exact mass
459.1305
Mol weight
460.0502
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
 DG01745  Anticholinergic antiparkinson agent
Remark
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Antiparkinsonian, Anticholinergic
  Disease
Parkinsonism [DS:H01600]
Target
muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Salivary secretion
Gastric acid secretion
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA10 Mazaticol
      D03264  Mazaticol hydrochloride hydrate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1169  Others
     D03264  Mazaticol hydrochloride hydrate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Mazaticol
      D03264  Mazaticol hydrochloride hydrate (JAN)
Neurological agents [br08367.html]
 Antiparkinson agents
  D03264
BRITE hierarchy
Other DBs
PubChem: 
LigandBox: 
KCF data Show

ATOM        29
            1   C1y C    32.4800  -20.0200
            2   N1y N    31.9200  -17.2200
            3   C1z C    33.3900  -20.6500
            4   C1x C    31.2200  -20.0200
            5   C1y C    31.9200  -18.6900
            6   C1x C    34.5100  -18.6900
            7   C1y C    30.3100  -20.5800
            8   C1x C    33.1800  -19.3900
            9   C1x C    30.6600  -19.3900
            10  O7a O    29.1900  -19.9500
            11  C7a C    28.0700  -20.5800
            12  O6a O    28.0700  -21.8400
            13  C1a C    32.6900  -21.9100
            14  C1a C    34.6500  -21.3500
            15  C1d C    26.9500  -19.9500
            16  C8y C    26.9500  -18.6200
            17  C8y C    25.8300  -20.5800
            18  O1a O    25.8300  -19.1100
            19  C8x C    28.0000  -17.9200
            20  C8x C    27.5800  -16.6600
            21  C8x C    26.3200  -16.6600
            22  S2x S    25.9000  -17.8500
            23  S2x S    24.6400  -20.0200
            24  C8x C    23.7300  -21.0000
            25  C8x C    24.4300  -22.1200
            26  C8x C    25.6900  -21.8400
            27  C1a C    31.9200  -15.7500
            28  X   Cl   38.8500  -18.7600
            29  O0  O    43.3300  -18.7600
BOND        30
            1     3  13 1
            2     3  14 1
            3     1   2 1
            4    11  15 1
            5     1   3 1
            6    15  16 1
            7     1   4 1
            8    15  17 1
            9     2   5 1
            10   15  18 1
            11    3   6 1
            12    4   7 1
            13    5   8 1
            14    5   9 1
            15   16  19 2
            16   19  20 1
            17   20  21 2
            18   21  22 1
            19   22  16 1
            20    7  10 1
            21   10  11 1
            22   11  12 2
            23    6   8 1
            24   17  23 1
            25   23  24 1
            26   24  25 2
            27   25  26 1
            28   26  17 2
            29    7   9 1
            30    2  27 1

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