KEGG   DRUG: D03264Help
Entry
D03264                      Drug                                   

Name
Mazaticol hydrochloride hydrate (JAN);
Mazaticol hydrochloride;
Pentona (TN)
Formula
C21H27NO3S2. HCl. H2O
Exact mass
459.1305
Mol weight
460.0502
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiparkinsonian
Remark
Therapeutic category: 
ATC code: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1169  Others
     D03264  Mazaticol hydrochloride hydrate (JAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA10 Mazaticol
      D03264  Mazaticol hydrochloride hydrate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
     Mazaticol [ATC:N04AA10]
      D03264  Mazaticol hydrochloride hydrate (JAN)
BRITE hierarchy
Other DBs
PubChem: 
LigandBox: 
KCF data Show

ATOM        29
            1   C1y C    32.4800  -20.0200
            2   N1y N    31.9200  -17.2200
            3   C1z C    33.3900  -20.6500
            4   C1x C    31.2200  -20.0200
            5   C1y C    31.9200  -18.6900
            6   C1x C    34.5100  -18.6900
            7   C1y C    30.3100  -20.5800
            8   C1x C    33.1800  -19.3900
            9   C1x C    30.6600  -19.3900
            10  O7a O    29.1900  -19.9500
            11  C7a C    28.0700  -20.5800
            12  O6a O    28.0700  -21.8400
            13  C1a C    32.6900  -21.9100
            14  C1a C    34.6500  -21.3500
            15  C1d C    26.9500  -19.9500
            16  C8y C    26.9500  -18.6200
            17  C8y C    25.8300  -20.5800
            18  O1a O    25.8300  -19.1100
            19  C8x C    28.0000  -17.9200
            20  C8x C    27.5800  -16.6600
            21  C8x C    26.3200  -16.6600
            22  S2x S    25.9000  -17.8500
            23  S2x S    24.6400  -20.0200
            24  C8x C    23.7300  -21.0000
            25  C8x C    24.4300  -22.1200
            26  C8x C    25.6900  -21.8400
            27  C1a C    31.9200  -15.7500
            28  X   Cl   38.8500  -18.7600
            29  O0  O    43.3300  -18.7600
BOND        30
            1     3  13 1
            2     3  14 1
            3     1   2 1
            4    11  15 1
            5     1   3 1
            6    15  16 1
            7     1   4 1
            8    15  17 1
            9     2   5 1
            10   15  18 1
            11    3   6 1
            12    4   7 1
            13    5   8 1
            14    5   9 1
            15   16  19 2
            16   19  20 1
            17   20  21 2
            18   21  22 1
            19   22  16 1
            20    7  10 1
            21   10  11 1
            22   11  12 2
            23    6   8 1
            24   17  23 1
            25   23  24 1
            26   24  25 2
            27   25  26 1
            28   26  17 2
            29    7   9 1
            30    2  27 1

» Japanese version   » Back

DBGET integrated database retrieval system