KEGG   DRUG: D03276Help
Entry
D03276                      Drug                                   

Name
Profenamine hibenzate (JAN);
Parkin (TN)
Formula
C19H24N2S. C14H10O4
Exact mass
554.2239
Mol weight
554.6991
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiparkinsonian
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Phenothiazines
Antiparkinsonian agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA05 Profenamine
      D03276  Profenamine hibenzate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1163  Profenamines
     D03276  Profenamine hibenzate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Profenamine
      D03276  Profenamine hibenzate (JAN)
BRITE hierarchy
Other DBs
PubChem: 
LigandBox: 
KCF data Show

ATOM        40
            1   C8y C     4.2000  -19.3900
            2   C8y C     4.2000  -20.7900
            3   S2x S     5.3900  -21.4900
            4   C8y C     6.6500  -20.7900
            5   C8y C     6.6500  -19.3900
            6   N1y N     5.3900  -18.6900
            7   C8x C     7.8400  -21.4900
            8   C8x C     9.0300  -20.7900
            9   C8x C     9.0300  -19.3900
            10  C8x C     7.8400  -18.6900
            11  C8x C     3.0100  -18.6900
            12  C8x C     1.7500  -19.3900
            13  C8x C     1.7500  -20.7900
            14  C8x C     3.0100  -21.4900
            15  C1b C     5.3900  -17.2900
            16  C1c C     6.6500  -16.5900
            17  N1c N     6.6500  -15.1900
            18  C1b C     7.8400  -14.4900
            19  C1a C     8.9600  -15.1900
            20  C1a C     7.8400  -17.2900
            21  C1b C     5.4600  -14.4900
            22  C1a C     4.2700  -15.1900
            23  C8x C    14.2100  -19.3200
            24  C8x C    14.2100  -20.7200
            25  C8x C    15.4700  -21.4200
            26  C8x C    16.6600  -20.7200
            27  C8y C    16.6600  -19.3200
            28  C8y C    15.4700  -18.6200
            29  C5a C    17.8500  -18.6200
            30  C8y C    19.1100  -19.3200
            31  C8x C    19.1100  -20.7200
            32  C8x C    20.3000  -21.4200
            33  C8y C    21.4900  -20.7200
            34  C8x C    21.4900  -19.3200
            35  C8x C    20.3000  -18.6200
            36  C6a C    15.4700  -17.2200
            37  O6a O    16.6600  -16.5200
            38  O6a O    14.2100  -16.5200
            39  O5a O    17.8500  -17.2200
            40  O1a O    22.7053  -21.4151
BOND        43
            1     1   2 2
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12    1  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16    2  14 1
            17    6  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   16  20 1
            23   17  21 1
            24   21  22 1
            25   29  39 2
            26   29  30 1
            27   23  24 2
            28   24  25 1
            29   25  26 2
            30   26  27 1
            31   27  28 2
            32   30  31 2
            33   31  32 1
            34   32  33 2
            35   33  34 1
            36   34  35 2
            37   35  30 1
            38   28  23 1
            39   28  36 1
            40   36  37 1
            41   27  29 1
            42   36  38 2
            43   33  40 1

» Japanese version   » Back

DBGET integrated database retrieval system