KEGG   DRUG: Diphenhydramine tannateHelp
Entry
D03285                      Drug                                   

Name
Diphenhydramine tannate (JP17);
Restamin A (TN)
Class
Anti-allergic agent
 DG01557  Histamine receptor antagonist
  DG01482  Histamine receptor H1 antagonist
Cyp substrate
 DG01644  CYP2D6 substrate
Cyp inhibitor
 DG01645  CYP2D6 inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antihistaminic
Target
histamine receptor H1 [HSA:3269] [KO:K04149]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Metabolism
Enzyme: CYP2D6 [HSA:1565]
Interaction
CYP inhibition: CYP2D6 [HSA:1565]
Drug interaction
Structure map
Hypnotics
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
   D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
    D04AA Antihistamines for topical use
     D04AA32 Diphenhydramine
      D03285  Diphenhydramine tannate (JP17)
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AA Aminoalkyl ethers
     R06AA02 Diphenhydramine
      D03285  Diphenhydramine tannate (JP17)
USP drug classification [BR:br08302]
 Antiemetics
  Antiemetics, Other
   Diphenhydramine
    D03285  Diphenhydramine tannate (JP17)
 Antiparkinson Agents
  Anticholinergics
   Diphenhydramine
    D03285  Diphenhydramine tannate (JP17)
 Respiratory Tract/Pulmonary Agents
  Antihistamines
   Diphenhydramine
    D03285  Diphenhydramine tannate (JP17)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Diphenhydramine
    D03285  Diphenhydramine tannate (JP17)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Diphenhydramine
      D03285  Diphenhydramine tannate (JP17)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP2D6
   Diphenhydramine
    D03285  Diphenhydramine tannate (JP17)
 CYP substrates
  CYP2D6
   Diphenhydramine
    D03285  Diphenhydramine tannate (JP17)
 Transporter inhibitors
  SLC22A2
   Diphenhydramine
    D03285  Diphenhydramine tannate (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D03285  Diphenhydramine tannate
BRITE hierarchy
Other DBs
PubChem: 
DrugBank: 

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