KEGG   DRUG: D03431Help
Entry
D03431                      Drug                                   

Name
Cefuroxime pivoxetil (USAN)
Formula
C23H28N4O11S
Exact mass
568.1475
Mol weight
568.5536
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: intermediate spectrum cephalosporin
prodrug, active substance: Cefuroxime [DR:D00262]
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DC Second-generation cephalosporins
     J01DC02 Cefuroxime
      D03431  Cefuroxime pivoxetil (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA27 Cefuroxime
      D03431  Cefuroxime pivoxetil (USAN)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefuroxime
    D03431  Cefuroxime pivoxetil (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefuroxime
      D03431  Cefuroxime pivoxetil (USAN)
BRITE hierarchy
Other DBs
CAS: 
100680-33-9
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        39
            1   C1y C    32.5159  -16.7317
            2   N1y N    32.5159  -18.1006
            3   C2y C    33.7017  -18.7850
            4   C2y C    34.8871  -18.1006
            5   C1x C    34.8871  -16.7317
            6   S2x S    33.7017  -16.0472
            7   C1y C    31.1469  -16.7317
            8   C5x C    31.1469  -18.1006
            9   N1b N    29.9615  -16.0472
            10  C5a C    28.7759  -16.7317
            11  O5a O    28.7759  -18.1006
            12  O5x O    29.9615  -18.7850
            13  C2c C    27.5903  -16.0472
            14  C1b C    36.0907  -18.7959
            15  C7a C    33.7017  -21.1833
            16  O7a O    32.4994  -21.8775
            17  O6a O    34.8705  -21.8583
            18  C8y C    26.3858  -16.7431
            19  O2x O    25.2563  -15.9478
            20  C8x C    24.1464  -16.7765
            21  C8x C    24.5914  -18.0881
            22  C8x C    25.9764  -18.1403
            23  N2b N    27.5902  -14.6574
            24  O7a O    37.2931  -18.1023
            25  C7a C    38.4552  -18.7738
            26  N1a N    39.6253  -18.0985
            27  O6a O    38.4548  -20.1496
            28  C1c C    31.3212  -21.1969
            29  O7a O    30.1666  -21.8633
            30  C7a C    28.9936  -21.1857
            31  C1d C    27.8294  -21.8575
            32  C1a C    31.3209  -19.8036
            33  O6a O    28.9938  -19.8035
            34  C1a C    26.6186  -22.5566
            35  O2a O    27.1414  -20.6660
            36  C1a C    28.5396  -23.0875
            37  C1a C    25.7323  -20.6658
            38  O2a O    28.8066  -13.9551
            39  C1a C    28.8066  -12.5551
BOND        41
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 1
            18   15  17 2
            19   13  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   18  22 2
            25   13  23 2
            26   14  24 1
            27   24  25 1
            28   25  26 1
            29   25  27 2
            30   16  28 1
            31   28  29 1
            32   29  30 1
            33   30  31 1
            34   28  32 1
            35   30  33 2
            36   31  34 1
            37   31  35 1
            38   31  36 1
            39   35  37 1
            40   23  38 1
            41   38  39 1

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