| Entry |
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| Name |
Chlorothiazide sodium (USP);
Diuril (TN)
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| Product |
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| Generic |
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| Formula |
C7H5ClN3O4S2. Na
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| Exact mass |
316.9308
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| Mol weight |
317.7051
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| Structure |
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| Activity |
Diuretic;
Antihypertensive
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| Remark |
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| Target |
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| Interaction |
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| Structure map |
| Sulfonamide derivatives - diuretics |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03A LOW-CEILING DIURETICS, THIAZIDES
C03AA Thiazides, plain
C03AA04 Chlorothiazide
D03471 Chlorothiazide sodium (USP)
USP drug classification [BR:br08302]
Cardiovascular Agents
Diuretics, Thiazide
Chlorothiazide
D03471 Chlorothiazide sodium (USP)
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 [HSA:6559] [KO:K14426] [TC:2.A.30.4.2]
Chlorothiazide [ATC:C03AA04]
D03471 Chlorothiazide sodium (USP)
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| Other DBs |
CAS: 7085-44-1 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 18
1 C8y C 19.8888 -15.0612
2 C8y C 19.8945 -16.4185
3 C8x C 21.0647 -14.3768
4 S2x S 18.7069 -14.3943
5 C8x C 21.0704 -17.0913
6 N5x N 18.7303 -17.1087
7 C8y C 22.2406 -15.0495
8 N4x N 17.5370 -15.0846 #-
9 O3c O 17.3848 -13.5811
10 O3c O 19.9297 -13.5577
11 C8y C 22.2464 -16.4068
12 C8x C 17.5487 -16.4418
13 S4a S 23.4165 -14.3651
14 X Cl 23.4282 -17.0796
15 N1a N 24.6567 -13.5168
16 O3c O 24.5456 -15.3714
17 O3c O 22.3283 -13.3295
18 Z Na 14.0700 -15.1900 #+
BOND 18
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 1
8 4 9 2
9 4 10 2
10 5 11 2
11 6 12 2
12 7 13 1
13 11 14 1
14 13 15 1
15 13 16 2
16 13 17 2
17 7 11 1
18 8 12 1
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