KEGG   DRUG: Chlorpheniramine polistirexHelp
Entry
D03475                      Drug                                   

Name
Chlorpheniramine polistirex (USAN)
Class
Anti-allergic agent
 DG01557  Histamine receptor antagonist
  DG01482  Histamine receptor H1 antagonist
Cyp substrate
 DG01644  CYP2D6 substrate
Cyp inhibitor
 DG01645  CYP2D6 inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antihistaminic
Target
H1-receptor [HSA:3269] [KO:K04149]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AB Substituted alkylamines
     R06AB04 Chlorphenamine
      D03475  Chlorpheniramine polistirex (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Chlorphenamine
      D03475  Chlorpheniramine polistirex (USAN)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP2D6
   Chlorphenamine
    D03475  Chlorpheniramine polistirex (USAN)
 CYP substrates
  CYP2D6
   Chlorphenamine
    D03475  Chlorpheniramine polistirex (USAN)
  CYP3A4
   Chlorphenamine
    D03475  Chlorpheniramine polistirex (USAN)
  CYP3A5
   Chlorphenamine
    D03475  Chlorpheniramine polistirex (USAN)
  CYP3A7
   Chlorphenamine
    D03475  Chlorpheniramine polistirex (USAN)
BRITE hierarchy
Other DBs
PubChem: 

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