KEGG   DRUG: D03478Help
Entry
D03478                      Drug                                   

Name
Choriogonadotropin alfa (USAN/INN);
Ovidrel (TN)
Product
Sequence
(alpha-subunit) APDVQDCPEC TLQENPFFSQ PGAPILQCMG CCFSRAYPTP
LRSKKTMLVQ KNVTSESTCC VAKSYNRVTV MGGFKVENHT ACHCSTCYYH KS
(Glycosylation site: 52; 78)
(beta-subunit) SKEPLRPRCR PINATLAVEK EGCPVCITVN TTICAGYCPT
MTRVLQGVLP ALPQVVCNYR DVRFESIRLP GCPRGVNPVV SYAVALSCQC ALCRRSTTDC
GGPKDHPLTC DDPRFQDSSS SKAPPPSLPS PSRLPGPSDT PILPQ
(Glycosylation site: 13; 30; 121; 127; 132; 138)
  Type
Peptide
Activity
Treatment of infertility;
Cryptorchidism therapy adjuvant [recombinant human chorionic gonadotropin (rhCG)]
Remark
ATC code: 
Comment
Gonadotropin, chorionic (human alfa-subunit protein moiety reduced), complex with chorionic gonadotropin (human beta-subunit protein moiety reduced)
alfa-Subunit [DR:D04429]
beta-Subunit (CAS 56832-34-9)
Target
luteinizing hormone/choriogonadotropin receptor agonist [HSA:3973] [KO:K04248]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS
    G03GA Gonadotropins
     G03GA08 Choriogonadotropin alfa
      D03478  Choriogonadotropin alfa (USAN/INN)
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Pituitary)
  Chorionic Gonadotropin
   D03478  Choriogonadotropin alfa (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Lutropin-choriogonadotropic hormone
    luteinizing hormone/choriogonadotropin receptor
     Choriogonadotropin alfa
      D03478  Choriogonadotropin alfa (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
177073-44-8
PubChem: 
DrugBank: 

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