KEGG   DRUG: D03478Help
Entry
D03478                      Drug                                   

Name
Choriogonadotropin alfa (genetical recombination) (JAN);
Choriogonadotropin alfa (USAN/INN);
Ovidrel (TN)
Product
Sequence
(alpha-subunit) APDVQDCPEC TLQENPFFSQ PGAPILQCMG CCFSRAYPTP
LRSKKTMLVQ KNVTSESTCC VAKSYNRVTV MGGFKVENHT ACHCSTCYYH KS
(Glycosylation site: 52; 78)
(beta-subunit) SKEPLRPRCR PINATLAVEK EGCPVCITVN TTICAGYCPT
MTRVLQGVLP ALPQVVCNYR DVRFESIRLP GCPRGVNPVV SYAVALSCQC ALCRRSTTDC
GGPKDHPLTC DDPRFQDSSS SKAPPPSLPS PSRLPGPSDT PILPQ
(Glycosylation site: 13; 30; 121; 127; 132; 138)
  Type
Peptide
Activity
Treatment of infertility;
Cryptorchidism therapy adjuvant [recombinant human chorionic gonadotropin (rhCG)]
Remark
ATC code: 
Comment
Gonadotropin, chorionic (human alfa-subunit protein moiety reduced), complex with chorionic gonadotropin (human beta-subunit protein moiety reduced)
alfa-Subunit [DR:D04429]
beta-Subunit (CAS 56832-34-9)
Target
luteinizing hormone/choriogonadotropin receptor agonist [HSA:3973] [KO:K04248]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS
    G03GA Gonadotropins
     G03GA08 Choriogonadotropin alfa
      D03478  Choriogonadotropin alfa (genetical recombination) (JAN); Choriogonadotropin alfa (USAN/INN)
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Pituitary)
  Chorionic Gonadotropin
   D03478  Choriogonadotropin alfa (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Lutropin-choriogonadotropic hormone
    luteinizing hormone/choriogonadotropin receptor
     Choriogonadotropin alfa
      D03478  Choriogonadotropin alfa (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
177073-44-8
PubChem: 
DrugBank: 

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