KEGG   DRUG: D03490Help
Entry
D03490                      Drug                                   

Name
Cicloprolol hydrochloride (USAN)
Formula
C18H29NO4. HCl
Exact mass
359.1863
Mol weight
359.8881
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-adrenergic [beta-receptor]
Remark
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Cicloprolol
      D03490  Cicloprolol hydrochloride (USAN)
    beta2-adrenergic receptor
     Cicloprolol
      D03490  Cicloprolol hydrochloride (USAN)
    beta3-adrenergic receptor
     Cicloprolol
      D03490  Cicloprolol hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
63686-79-3
PubChem: 
LigandBox: 
KCF data Show

ATOM        24
            1   O2a O    19.4600  -16.8700
            2   C1b C    20.7200  -16.1700
            3   C1c C    21.9100  -16.8700
            4   C1b C    23.1000  -16.1700
            5   O1a O    21.9100  -18.2700
            6   N1b N    24.2900  -16.8700
            7   C1c C    25.4800  -16.1700
            8   C1a C    26.6700  -16.8700
            9   C1a C    25.4800  -14.7700
            10  C8y C    19.4600  -18.2700
            11  C8x C    18.2000  -18.9700
            12  C8x C    18.2000  -20.3700
            13  C8y C    19.3900  -21.0700
            14  C8x C    20.6500  -20.3700
            15  C8x C    20.6500  -18.9700
            16  O2a O    19.3900  -22.4700
            17  C1b C    18.2000  -23.1700
            18  C1b C    17.0100  -22.4700
            19  O2a O    15.7500  -23.1700
            20  C1b C    14.5600  -22.4000
            21  C1y C    13.3700  -23.1000
            22  C1x C    11.9700  -23.1000
            23  C1x C    12.6700  -24.2900
            24  X   Cl   26.1800  -21.7000
BOND        24
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     3   5 1
            5     4   6 1
            6     6   7 1
            7     7   8 1
            8     7   9 1
            9     1  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14  15 2
            15   10  15 1
            16   13  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   22  21 1
            23   23  22 1
            24   21  23 1

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