KEGG   DRUG: Cicloprolol hydrochlorideHelp
Entry
D03490                      Drug                                   

Name
Cicloprolol hydrochloride (USAN)
Formula
C18H29NO4. HCl
Exact mass
359.1863
Mol weight
359.8881
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Activity
Anti-adrenergic [beta-receptor]
Target
beta1-adrenergic receptor [HSA:153] [KO:K04141];
beta2-adrenergic receptor [HSA:154] [KO:K04142];
beta3-adrenergic receptor [HSA:155] [KO:K04143]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Cicloprolol
      D03490  Cicloprolol hydrochloride (USAN)
    beta2-adrenergic receptor
     Cicloprolol
      D03490  Cicloprolol hydrochloride (USAN)
    beta3-adrenergic receptor
     Cicloprolol
      D03490  Cicloprolol hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
63686-79-3
PubChem: 
LigandBox: 
KCF data Show

ATOM        24
            1   O2a O    19.4600  -16.8700
            2   C1b C    20.7200  -16.1700
            3   C1c C    21.9100  -16.8700
            4   C1b C    23.1000  -16.1700
            5   O1a O    21.9100  -18.2700
            6   N1b N    24.2900  -16.8700
            7   C1c C    25.4800  -16.1700
            8   C1a C    26.6700  -16.8700
            9   C1a C    25.4800  -14.7700
            10  C8y C    19.4600  -18.2700
            11  C8x C    18.2000  -18.9700
            12  C8x C    18.2000  -20.3700
            13  C8y C    19.3900  -21.0700
            14  C8x C    20.6500  -20.3700
            15  C8x C    20.6500  -18.9700
            16  O2a O    19.3900  -22.4700
            17  C1b C    18.2000  -23.1700
            18  C1b C    17.0100  -22.4700
            19  O2a O    15.7500  -23.1700
            20  C1b C    14.5600  -22.4000
            21  C1y C    13.3700  -23.1000
            22  C1x C    11.9700  -23.1000
            23  C1x C    12.6700  -24.2900
            24  X   Cl   26.1800  -21.7000
BOND        24
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     3   5 1
            5     4   6 1
            6     6   7 1
            7     7   8 1
            8     7   9 1
            9     1  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14  15 2
            15   10  15 1
            16   13  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   22  21 1
            23   23  22 1
            24   21  23 1

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