KEGG   DRUG: DapiclerminHelp
Entry
D03647                      Drug                                   

Name
Dapiclermin (USAN/INN);
Axokine (TN)
Formula
C945H1482N266O278S3
Exact mass
21100.9169
Mol weight
21113.689
Sequence
AFTEHSPLTP HRRDLASRSI WLARKIRSDL TALTESYVKH QGLNKNINLD SADGMPVAST
DRWSELTEAE RLQENLQAYR TFHVLLARLL EDQQVHFTPT EGDFHQAIHT LLLQVAAFAY
QIEELMILLE YKIPRNEADG MPINVGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRFISS
HQTG
  Type
Peptide
Class
Other
 DG01706  Antiobesity
Efficacy
Antiobesity
Comment
Treatment of overweight and obesity
Target
AMPK (PRKAA) [HSA:5562 5563] [KO:K07198]
  Pathway
hsa04140  Autophagy - animal
hsa04150  mTOR signaling pathway
hsa04910  Insulin signaling pathway
hsa04920  Adipocytokine signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Serine/threonine kinases
   CAMKL family
    AMPK (PRKAA)
     D03647  Dapiclermin (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 444069-80-1
PubChem: 17397746

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