| Entry |
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| Name |
Denileukin diftitox (USAN/INN);
Ontak (TN)
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| Product |
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| Formula |
C2560H4036N678O799S17
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| Exact mass |
57605.128
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| Mol weight |
57640.606
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| Activity |
Biological response modifier;
Antineoplastic
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| Remark |
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| Comment |
Indication: recurrent cutaneous T-cell lymphoma
Denileukin diftitox consists of diphtheria toxin fragments fused to interleukin-2.
immunotoxin
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| Target |
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| Pathway |
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| Interaction |
Genomic biomarker: CD25 [HSA: 3669] expression
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01X OTHER ANTINEOPLASTIC AGENTS
L01XX Other antineoplastic agents
L01XX29 Denileukin diftitox
D03682 Denileukin diftitox (USAN/INN)
Target-based classification of drugs [BR:br08310]
Cytokine receptors
Class I cytokine receptors (hematopoietin family receptors)
interleukin 2 receptor [HSA:3559 3560 3561] [KO:K05068 K05069 K05070]
Denileukin diftitox [ATC:L01XX29]
D03682 Denileukin diftitox (USAN/INN)
Antineoplastics [BR:br08308]
Molecularly targeted agents
Interleukin 2 receptor toxin
Denileukin diftitox [ATC:L01XX29]
D03682 Denileukin diftitox (USAN/INN)
Biologic response modifiers
Interleukins
Denileukin diftitox [ATC:L01XX29]
D03682 Denileukin diftitox (USAN/INN)
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| Other DBs |
CAS: 173146-27-5 PubChem: DrugBank: |
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