KEGG   DRUG: D03740Help
Entry
D03740                      Drug                                   

Name
Dextroamphetamine (USAN);
Dexamfetamine (INN)
Formula
C9H13N
Exact mass
135.1048
Mol weight
135.2062
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Stimulant [central]
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Compoment of Biphetamine (TN)
Target
noradrenalin transporter inhibitor [HSA:6530] [KO:K05035];
dopamine transporter inhibitor [HSA:6531] [KO:K05036];
serotonin transporter inhibitor [HSA:6532] [KO:K05037]
  Pathway
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
hsa05031  Amphetamine addiction  
 
Metabolism
Enzyme: CYP2D6 [HSA:1565]
Interaction
Drug interaction
Structure map
Neurotransmitter transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
    N06BA Centrally acting sympathomimetics
     N06BA02 Dexamfetamine
      D03740  Dextroamphetamine (USAN); Dexamfetamine (INN)
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Attention Deficit Hyperactivity Disorder Agents, Amphetamines
   Dextroamphetamine
    D03740  Dextroamphetamine (USAN); Dexamfetamine (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (noradrenalin transporter)
     Dexamfetamine
      D03740  Dextroamphetamine (USAN); Dexamfetamine (INN)
    SLC6A3 (dopamine transporter)
     Dexamfetamine
      D03740  Dextroamphetamine (USAN); Dexamfetamine (INN)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP2D6
   Dexamfetamine
    D03740  Dextroamphetamine (USAN); Dexamfetamine (INN)
BRITE hierarchy
Other DBs
CAS: 
51-64-9
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        10
            1   C8y C    18.0880  -15.4844
            2   C8x C    16.8267  -14.7837
            3   C8x C    18.0880  -16.8859
            4   C1b C    19.2792  -14.7837
            5   C8x C    15.6355  -15.4844
            6   C8x C    16.8267  -17.5866
            7   C1c C    20.4704  -15.4844
            8   C8x C    15.6355  -16.8859
            9   N1a N    21.6616  -14.7837
            10  C1a C    20.4704  -16.8859
BOND        10
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     7   9 1
            9     7  10 1 #Up
            10    6   8 1

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