KEGG   DRUG: D03746Help
Entry
D03746                      Drug                                   

Name
Dextrorphan hydrochloride (USAN)
Formula
C17H23NO. HCl
Exact mass
293.1546
Mol weight
293.8316
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Vasospastic therapy adjunct
Remark
Drug group: 
Target
N-methyl-D-aspartate receptor antagonist [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04720  Long-term potentiation
hsa04724  Glutamatergic synapse  
 
Interaction
Drug interaction
Structure map
N-Metyl-D-aspartic acid receptor antagonists
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Dextrorphan
      D03746  Dextrorphan hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
69376-27-8
PubChem: 
LigandBox: 
KCF data Show

ATOM        20
            1   C1z C    32.7439  -19.3484
            2   C8y C    32.7555  -18.0054
            3   C1y C    33.8882  -20.0375
            4   C1x C    34.0284  -18.4960
            5   C1x C    31.5642  -19.9967
            6   C8y C    33.9232  -17.3457
            7   C8x C    31.5876  -17.3223
            8   C1y C    35.0794  -19.3251
            9   C1x C    33.8767  -21.3805
            10  C1x C    36.2589  -18.5135
            11  C1x C    31.5409  -21.3455
            12  C1x C    35.0911  -18.0405
            13  C8x C    33.9408  -16.0027
            14  C8y C    31.5993  -15.9734
            15  N1y N    36.2474  -19.9908
            16  C1x C    32.6971  -22.0288
            17  C8x C    32.7905  -15.3137
            18  O1a O    30.4432  -15.2903
            19  C1a C    37.6253  -20.0024
            20  X   Cl   41.9300  -18.9000
BOND        22
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     1   5 1
            5     2   6 2
            6     2   7 1
            7     3   8 1
            8     3   9 1
            9     4  10 1
            10    5  11 1
            11    6  12 1
            12    6  13 1
            13    7  14 2
            14    8  15 1 #Down
            15    9  16 1
            16   13  17 2
            17   14  18 1
            18   15  19 1
            19    8  12 1
            20   10  15 1
            21   11  16 1
            22   14  17 1

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