KEGG   DRUG: Dextrorphan hydrochlorideHelp
Entry
D03746                      Drug                                   

Name
Dextrorphan hydrochloride (USAN)
Formula
C17H23NO. HCl
Exact mass
293.1546
Mol weight
293.8316
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01498  NMDA receptor antagonist
Activity
Antitussive, NMDA antagonist
Comment
Opioid alkaloid derivative, morphinan
Vasospastic therapy adjunct
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Long-term potentiation
Glutamatergic synapse
Interaction
Drug interaction
Structure map
N-Metyl-D-aspartic acid receptor antagonists
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Dextrorphan
      D03746  Dextrorphan hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
69376-27-8
PubChem: 
LigandBox: 
KCF data Show

ATOM        20
            1   C1z C    32.7439  -19.3484
            2   C8y C    32.7555  -18.0054
            3   C1y C    33.8882  -20.0375
            4   C1x C    34.0284  -18.4960
            5   C1x C    31.5642  -19.9967
            6   C8y C    33.9232  -17.3457
            7   C8x C    31.5876  -17.3223
            8   C1y C    35.0794  -19.3251
            9   C1x C    33.8767  -21.3805
            10  C1x C    36.2589  -18.5135
            11  C1x C    31.5409  -21.3455
            12  C1x C    35.0911  -18.0405
            13  C8x C    33.9408  -16.0027
            14  C8y C    31.5993  -15.9734
            15  N1y N    36.2474  -19.9908
            16  C1x C    32.6971  -22.0288
            17  C8x C    32.7905  -15.3137
            18  O1a O    30.4432  -15.2903
            19  C1a C    37.6253  -20.0024
            20  X   Cl   41.9300  -18.9000
BOND        22
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     1   5 1
            5     2   6 2
            6     2   7 1
            7     3   8 1
            8     3   9 1
            9     4  10 1
            10    5  11 1
            11    6  12 1
            12    6  13 1
            13    7  14 2
            14    8  15 1 #Down
            15    9  16 1
            16   13  17 2
            17   14  18 1
            18   15  19 1
            19    8  12 1
            20   10  15 1
            21   11  16 1
            22   14  17 1

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