KEGG   DRUG: D03747Help
Entry
D03747                      Drug                                   

Name
Ibrolipim (USAN/INN)
Formula
C19H20BrN2O4P
Exact mass
450.0344
Mol weight
451.2509
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiatherogenic;
Antiobesity;
Antidyslipidemia;
Anticachexia;
And antidiabetes/syndrome X
Target
lipoprotein lipase activator [HSA:4023] [KO:K01059]
  Pathway
hsa00561  Glycerolipid metabolism
hsa03320  PPAR signaling pathway  
 
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   lipoprotein lipase [HSA:4023] [KO:K01059]
    Ibrolipim
     D03747  Ibrolipim (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
133208-93-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C8x C     3.9200  -17.0100
            2   C8y C     3.9200  -15.6100
            3   C8x C     5.1100  -14.9100
            4   C8y C     6.3700  -15.6100
            5   C8y C     6.3700  -17.0100
            6   C8x C     5.1100  -17.7100
            7   N1b N     7.5600  -17.7100
            8   C5a C     8.8200  -17.0100
            9   C8y C    10.0100  -17.7100
            10  C8x C    11.2000  -17.0100
            11  C8x C    12.4600  -17.7100
            12  C8y C    12.4600  -19.1100
            13  C8x C    11.2000  -19.8100
            14  C8x C    10.0100  -19.1100
            15  C1b C    13.6500  -19.8100
            16  O5a O     8.8200  -15.6100
            17  C3b C     7.5600  -14.9100
            18  N3a N     8.8200  -14.2100
            19  X   Br    2.7300  -14.9100
            20  P1b P    14.8681  -19.1199
            21  O2b O    16.0805  -18.4199
            22  O2b O    15.5516  -20.3156
            23  O3b O    14.1622  -17.8850
            24  C1b C    16.9516  -20.3156
            25  C1a C    17.6419  -21.5113
            26  C1b C    17.3031  -19.1259
            27  C1a C    18.5125  -18.4278
BOND        28
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14   13  14 2
            15    9  14 1
            16   12  15 1
            17    8  16 2
            18    4  17 1
            19   17  18 3
            20    2  19 1
            21   15  20 1
            22   20  21 1
            23   20  22 1
            24   20  23 2
            25   22  24 1
            26   24  25 1
            27   21  26 1
            28   26  27 1

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