KEGG   DRUG: D03765Help
Entry
D03765                      Drug                                   

Name
Spirapril hydrochloride (USAN);
Renormax (TN)
Formula
C22H30N2O5S2. HCl
Exact mass
502.1363
Mol weight
503.0749
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Enzyme inhibitor [angiotensin-converting]
Remark
ATC code: 
Drug group: 
Target
angiotensin-converting enzyme (ACE) inhibitor [HSA:1636] [KO:K01283]
  Pathway
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09A ACE INHIBITORS, PLAIN
    C09AA ACE inhibitors, plain
     C09AA11 Spirapril
      D03765  Spirapril hydrochloride (USAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   angiotensin-converting enzyme (ACE)
    Spirapril
     D03765  Spirapril hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
94841-17-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        32
            1   N1y N    33.3340  -17.8513
            2   C5a C    32.1482  -18.5488
            3   C1c C    30.9623  -17.8513
            4   O5a O    32.1482  -19.9439
            5   N1b N    29.7067  -18.5488
            6   C1a C    30.9623  -16.4562
            7   C1c C    28.5209  -17.8513
            8   C7a C    28.5209  -16.4562
            9   C1b C    27.3351  -18.5488
            10  O7a O    29.7067  -15.7586
            11  O6a O    27.3351  -15.7586
            12  C1b C    26.0795  -17.8513
            13  C1b C    29.7067  -14.3635
            14  C8y C    24.8936  -18.5488
            15  C1a C    28.5209  -13.6659
            16  C1y C    33.3340  -16.4513
            17  C1x C    34.6655  -18.2839
            18  C1z C    35.4884  -17.1513
            19  C1x C    34.6655  -16.0186
            20  S2x S    36.3098  -18.2846
            21  C1x C    37.6418  -17.8535
            22  C1x C    37.6434  -16.4535
            23  S2x S    36.3125  -16.0193
            24  C6a C    33.3340  -15.0513
            25  O6a O    34.5364  -14.3570
            26  O6a O    32.1105  -14.3449
            27  C8x C    23.6962  -17.8701
            28  C8x C    22.4893  -18.5798
            29  C8x C    22.5005  -19.9798
            30  C8x C    23.6980  -20.6584
            31  C8x C    24.9048  -19.9488
            32  X   Cl   41.7744  -18.1303
BOND        33
            1     1   2 1
            2     2   3 1
            3     2   4 2
            4     3   5 1
            5     3   6 1 #Up
            6     5   7 1
            7     7   8 1 #Up
            8     7   9 1
            9     8  10 1
            10    8  11 2
            11    9  12 1
            12   10  13 1
            13   12  14 1
            14   13  15 1
            15    1  16 1
            16    1  17 1
            17   17  18 1
            18   18  19 1
            19   16  19 1
            20   18  20 1
            21   20  21 1
            22   21  22 1
            23   22  23 1
            24   18  23 1
            25   16  24 1 #Down
            26   24  25 1
            27   24  26 2
            28   14  27 2
            29   27  28 1
            30   28  29 2
            31   29  30 1
            32   30  31 2
            33   14  31 1

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