KEGG   DRUG: D03814Help
Entry
D03814                      Drug                                   

Name
Atropine methylbromide (JAN)
Formula
C18H26NO3. Br
Exact mass
383.1096
Mol weight
384.3079
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic
Remark
ATC code: 
Drug group: 
Comment
Component of Stmerin-D (TN)
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03B BELLADONNA AND DERIVATIVES, PLAIN
    A03BB Belladonna alkaloids, semisynthetic, quaternary ammonium compounds
     A03BB02 Methylatropine
      D03814  Atropine methylbromide (JAN)
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Atropine
    D03814  Atropine methylbromide (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Category 2
  Inorganic and organic chemicals
   Methylatropine
    D03814  Atropine methylbromide (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Atropine
      D03814  Atropine methylbromide (JAN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D03814  Atropine methylbromide (JAN)
BRITE hierarchy
Other DBs
CAS: 
2870-71-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C1x C    28.3406  -36.2137
            2   C1x C    28.6601  -35.0727
            3   C1y C    29.4815  -35.9399
            4   C1y C    29.8010  -34.7989
            5   N2y N    28.5688  -33.5210 #+
            6   C1x C    31.3070  -35.9399
            7   C1x C    31.0332  -34.7989
            8   C1y C    32.3111  -36.4875
            9   O7a O    33.3608  -37.3546
            10  C7a C    34.5474  -37.3546
            11  C1c C    35.1408  -36.3049
            12  O6a O    35.1408  -38.4499
            13  C8y C    36.3274  -36.3049
            14  C1b C    34.5474  -35.3009
            15  O1a O    35.1408  -34.2512
            16  C8x C    37.0151  -37.4965
            17  C8x C    38.3783  -37.4968
            18  C8x C    39.0602  -36.3163
            19  C8x C    38.3726  -35.1247
            20  C8x C    37.0093  -35.1244
            21  C1a C    27.8394  -32.3679
            22  C1a C    27.3718  -34.1176
            23  X   Br   32.2709  -32.5515 #-
BOND        24
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 1
            13   11  14 1
            14   14  15 1
            15    4   5 1
            16    7   8 1
            17   13  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   13  20 1
            23    5  21 1
            24    5  22 1

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