| Entry |
|
|---|
| Name |
Rivastigmine (JAN/USAN/INN);
Exelon (TN)
|
|---|
| Product |
|
|---|
| Formula |
C14H22N2O2
|
|---|
| Exact mass |
250.1681
|
|---|
| Mol weight |
250.3367
|
|---|
| Structure |
     |
|---|
| Activity |
Treatment of Alzheimer's disease [acetylcholinesterase inhibitor] [DS: H00056]
|
|---|
| Remark |
Same as: Therapeutic category: ATC code: |
|---|
| Target |
acetylcholinesterase (AChE) inhibitor [HSA: 43] [KO: K01049]; butyrylcholinesterase (BChE) inhibitor [HSA: 590] [KO: K01050] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
119 Miscellaneous
1190 Miscellaneous
D03822 Rivastigmine (JAN/USAN/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06D ANTI-DEMENTIA DRUGS
N06DA Anticholinesterases
N06DA03 Rivastigmine
D03822 Rivastigmine (JAN/USAN/INN)
USP drug classification [BR:br08302]
Antidementia Agents
Cholinesterase Inhibitors
Rivastigmine
D03822 Rivastigmine (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases
acetylcholinesterase (AChE) [HSA:43] [KO:K01049]
Rivastigmine [ATC:N06DA03]
D03822 Rivastigmine (JAN/USAN/INN)
 |
|---|
| Other DBs |
CAS: 123441-03-2 PubChem: DrugBank: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 18
1 C8y C 33.4600 -18.9700
2 C8x C 34.6500 -18.2700
3 C8x C 33.4600 -20.3700
4 O7a O 32.2000 -18.2700
5 C8y C 35.8400 -18.9700
6 C8x C 34.6500 -21.0700
7 C7a C 31.0100 -18.9700
8 C8x C 35.8400 -20.3700
9 N1c N 29.8200 -18.2700
10 O6a O 31.0100 -20.3700
11 C1a C 28.5600 -18.9700
12 C1c C 37.1000 -18.2700
13 N1c N 38.2900 -18.9700
14 C1a C 37.1000 -16.8700
15 C1a C 38.2900 -20.3700
16 C1a C 39.4800 -18.2700
17 C1b C 29.8200 -16.8700
18 C1a C 31.0800 -16.1700
BOND 18
1 5 8 2
2 7 9 1
3 7 10 2
4 9 11 1
5 6 8 1
6 5 12 1
7 1 2 2
8 12 13 1
9 1 3 1
10 12 14 1 #Down
11 1 4 1
12 13 15 1
13 2 5 1
14 13 16 1
15 3 6 2
16 9 17 1
17 4 7 1
18 17 18 1
|
|---|
