KEGG   DRUG: D03878Help
Entry
D03878                      Drug                                   

Name
Dizocilpine maleate (USAN)
Formula
C16H15N. C4H4O4
Exact mass
337.1314
Mol weight
337.3692
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Neuroprotective
Target
N-methyl-D-aspartate receptor antagonist [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04720  Long-term potentiation
hsa04724  Glutamatergic synapse  
 
Interaction
Drug interaction
Structure map
N-Metyl-D-aspartic acid receptor antagonists
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
     Dizocilpine
      D03878  Dizocilpine maleate (USAN)
BRITE hierarchy
Other DBs
CAS: 
77086-22-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C2b C    36.4000  -14.2100
            2   C2b C    34.7200  -14.2100
            3   C6a C    37.0300  -15.4000
            4   C6a C    34.0900  -15.4000
            5   O6a O    36.4000  -16.5200
            6   O6a O    38.4300  -15.4000
            7   O6a O    32.6900  -15.4000
            8   O6a O    34.7200  -16.5200
            9   C1y C    24.9900  -17.6400
            10  C1x C    26.3900  -17.6400
            11  C1z C    25.6900  -14.6300
            12  C8y C    24.4300  -15.1900
            13  C8y C    24.1500  -16.5200
            14  C8x C    22.8200  -16.9400
            15  C8x C    21.7700  -16.0300
            16  C8x C    22.1200  -14.6300
            17  C8x C    23.4500  -14.2800
            18  C8y C    27.2300  -16.5900
            19  C8y C    26.9500  -15.1900
            20  C8x C    28.0000  -14.2800
            21  C8x C    29.2600  -14.7000
            22  C8x C    29.6100  -16.1000
            23  C8x C    28.5600  -17.0100
            24  N1x N    25.6900  -16.1700
            25  C1a C    25.6900  -13.2300
BOND        27
            1     1   2 2
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 2
            6     4   7 1
            7     4   8 2
            8    14  15 2
            9    15  16 1
            10   16  17 2
            11   17  12 1
            12    9  10 1
            13   10  18 1
            14    9  13 1
            15   19  11 1
            16   12  11 1
            17   18  19 2
            18   19  20 1
            19   20  21 2
            20   21  22 1
            21   22  23 2
            22   23  18 1
            23   12  13 2
            24   11  24 1 #Up
            25    9  24 1 #Up
            26   13  14 1
            27   11  25 1

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