KEGG   DRUG: Dizocilpine maleateHelp
Entry
D03878                      Drug                                   

Name
Dizocilpine maleate (USAN)
Formula
C16H15N. C4H4O4
Exact mass
337.1314
Mol weight
337.3692
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01498  NMDA receptor antagonist
Activity
Neuroprotectant
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Long-term potentiation
Glutamatergic synapse
Interaction
Drug interaction
Structure map
N-Metyl-D-aspartic acid receptor antagonists
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Dizocilpine
      D03878  Dizocilpine maleate (USAN)
BRITE hierarchy
Other DBs
CAS: 
77086-22-7
PubChem: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C2b C    36.4000  -14.2100
            2   C2b C    34.7200  -14.2100
            3   C6a C    37.0300  -15.4000
            4   C6a C    34.0900  -15.4000
            5   O6a O    36.4000  -16.5200
            6   O6a O    38.4300  -15.4000
            7   O6a O    32.6900  -15.4000
            8   O6a O    34.7200  -16.5200
            9   C1y C    24.9900  -17.6400
            10  C1x C    26.3900  -17.6400
            11  C1z C    25.6900  -14.6300
            12  C8y C    24.4300  -15.1900
            13  C8y C    24.1500  -16.5200
            14  C8x C    22.8200  -16.9400
            15  C8x C    21.7700  -16.0300
            16  C8x C    22.1200  -14.6300
            17  C8x C    23.4500  -14.2800
            18  C8y C    27.2300  -16.5900
            19  C8y C    26.9500  -15.1900
            20  C8x C    28.0000  -14.2800
            21  C8x C    29.2600  -14.7000
            22  C8x C    29.6100  -16.1000
            23  C8x C    28.5600  -17.0100
            24  N1x N    25.6900  -16.1700
            25  C1a C    25.6900  -13.2300
BOND        27
            1     1   2 2
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 2
            6     4   7 1
            7     4   8 2
            8    14  15 2
            9    15  16 1
            10   16  17 2
            11   17  12 1
            12    9  10 1
            13   10  18 1
            14    9  13 1
            15   19  11 1
            16   12  11 1
            17   18  19 2
            18   19  20 1
            19   20  21 2
            20   21  22 1
            21   22  23 2
            22   23  18 1
            23   12  13 2
            24   11  24 1 #Up
            25    9  24 1 #Up
            26   13  14 1
            27   11  25 1

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