KEGG   DRUG: Dobutamine lactobionateHelp
Entry
D03880                      Drug                                   

Name
Dobutamine lactobionate (USAN)
Formula
C12H22O12. C18H23NO3
Exact mass
659.2789
Mol weight
659.676
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01699  Catecholamine cardiotonic
 DG01456  Adrenergic receptor agonist
  DG01455  beta-Adrenergic receptor agonist
   DG01451  beta1-Adrenergic receptor agonist
Remark
ATC code: 
Chemical group: 
Activity
Cardiotonic
Target
beta1-adrenergic receptor [HSA:153] [KO:K04141]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Structure map
beta-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA07 Dobutamine
      D03880  Dobutamine lactobionate (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Dobutamine
      D03880  Dobutamine lactobionate (USAN)
BRITE hierarchy
Other DBs
CAS: 
104564-71-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        46
            1   C8y C    34.3215  -11.3144
            2   C8x C    35.5366  -10.6225
            3   C8x C    34.3158  -12.7157
            4   C1b C    33.1121  -10.6166
            5   C8y C    36.8161  -11.3260
            6   C8x C    35.5249  -13.4192
            7   C1b C    31.8969  -11.3144
            8   C8y C    36.8101  -12.7215
            9   O1a O    37.9613  -10.6342
            10  N1b N    30.6876  -10.6225
            11  O1a O    38.0195  -13.4249
            12  C1c C    29.4840  -11.3203
            13  C1b C    28.2688  -10.6225
            14  C1a C    29.4840  -12.7157
            15  C1b C    27.0593  -11.3203
            16  C8y C    25.8442  -10.6225
            17  C8x C    24.6407  -11.3203
            18  C8x C    25.8442   -9.2271
            19  C8x C    23.4254  -10.6225
            20  C8x C    24.6407   -8.5235
            21  C8y C    23.4254   -9.2271
            22  O1a O    22.2102   -8.5235
            23  C1c C    46.3934   -9.7245
            24  C1c C    47.5830   -9.0947
            25  C1c C    45.2039   -9.0248
            26  C1b C    43.9442   -9.7245
            27  O1a O    42.7546   -9.0248
            28  O1a O    45.2039   -7.6252
            29  C1c C    48.7726   -9.7245
            30  C6a C    50.0322   -9.0248
            31  O6a O    51.2219   -9.7245
            32  O6a O    50.0322   -7.6252
            33  C1y C    45.2039  -11.8938
            34  O2x O    44.0142  -11.1941
            35  C1y C    45.2039  -13.2233
            36  C1y C    42.8246  -11.8938
            37  C1y C    44.0142  -13.9231
            38  O1a O    46.4634  -13.9231
            39  C1y C    42.8246  -13.2233
            40  C1b C    41.5651  -11.1941
            41  O1a O    44.0142  -15.3226
            42  O1a O    41.5651  -13.9231
            43  O1a O    40.3754  -11.8938
            44  O2a O    46.3934  -11.1941
            45  O1a O    47.5830   -7.6252
            46  O1a O    48.7726  -11.1941
BOND        47
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     5   9 1
            9     7  10 1
            10    8  11 1
            11   10  12 1
            12   12  13 1
            13   12  14 1
            14   13  15 1
            15   15  16 1
            16   16  17 2
            17   16  18 1
            18   17  19 1
            19   18  20 2
            20   19  21 2
            21   21  22 1
            22    6   8 1
            23   20  21 1
            24   23  24 1
            25   23  25 1
            26   25  26 1
            27   26  27 1
            28   25  28 1 #Up
            29   24  29 1
            30   29  30 1
            31   30  31 1
            32   30  32 2
            33   33  34 1
            34   33  35 1
            35   34  36 1
            36   35  37 1
            37   35  38 1 #Down
            38   36  39 1
            39   36  40 1 #Up
            40   37  41 1 #Up
            41   39  42 1 #Up
            42   40  43 1
            43   37  39 1
            44   33  44 1 #Up
            45   23  44 1 #Down
            46   24  45 1 #Down
            47   29  46 1 #Down

» Japanese version   » Back

DBGET integrated database retrieval system