KEGG   DRUG: D03891Help
Entry
D03891                      Drug                                   

Name
Dopexamine (USAN/INN)
Formula
C22H32N2O2
Exact mass
356.2464
Mol weight
356.5017
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Cardiovascular agent
Remark
ATC code: 
Drug group: 
Target
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142];
dopamine D1 receptor agonist [HSA:1812] [KO:K04144];
dopamine D2 receptor agonist [HSA:1813] [KO:K04145];
dopamine D3 receptor agonist [HSA:1814] [KO:K04146];
dopamine D4 receptor agonist [HSA:1815] [KO:K04147];
dopamine D5 receptor agonist [HSA:1816] [KO:K05840]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04540  Gap junction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA14 Dopexamine
      D03891  Dopexamine (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor
     Dopexamine
      D03891  Dopexamine (USAN/INN)
   Dopamine
    dopamine D1-receptor
     Dopexamine
      D03891  Dopexamine (USAN/INN)
    dopamine D2-receptor
     Dopexamine
      D03891  Dopexamine (USAN/INN)
    dopamine D3-receptor
     Dopexamine
      D03891  Dopexamine (USAN/INN)
    dopamine D4-receptor
     Dopexamine
      D03891  Dopexamine (USAN/INN)
    dopamine D5-receptor
     Dopexamine
      D03891  Dopexamine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
86197-47-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C8y C    43.6800  -18.9700
            2   C8y C    43.6800  -20.3700
            3   C8x C    42.4200  -21.0700
            4   C8x C    41.2300  -20.3700
            5   C8y C    41.2300  -18.9700
            6   C8x C    42.4200  -18.2700
            7   O1a O    44.8700  -18.2700
            8   O1a O    44.8700  -21.0700
            9   C1b C    39.9700  -18.2700
            10  C1b C    38.7800  -18.9700
            11  N1b N    37.5900  -18.2700
            12  C1b C    36.4000  -18.9700
            13  C1b C    35.1400  -18.2700
            14  C1b C    33.9500  -18.9700
            15  C1b C    32.7600  -18.2700
            16  C1b C    31.5700  -18.9700
            17  C1b C    30.3800  -18.2700
            18  N1b N    29.1900  -18.9700
            19  C1b C    28.0000  -18.2700
            20  C1b C    26.7400  -18.9700
            21  C8y C    25.5500  -18.2700
            22  C8x C    24.3600  -18.9700
            23  C8x C    23.1700  -18.2700
            24  C8x C    23.1700  -16.8700
            25  C8x C    24.3600  -16.1700
            26  C8x C    25.5500  -16.8700
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     2   8 1
            9     5   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 2
            23   22  23 1
            24   23  24 2
            25   24  25 1
            26   25  26 2
            27   21  26 1

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