KEGG   DRUG: D03903Help
Entry
D03903                      Drug                                   

Name
Doxycycline calcium (USP)
Product
Formula
C22H20N2O8. 2Ca
Exact mass
520.0471
Mol weight
520.5588
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial;
Antiprotozoal [DS:H00310 H00322]
Remark
ATC code: 
Drug group: 
Comment
Component of Vibramycin (TN)
Semisynthetic tetracycline
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Tetracyclines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01A TETRACYCLINES
    J01AA Tetracyclines
     J01AA02 Doxycycline
      D03903  Doxycycline calcium (USP)
USP drug classification [BR:br08302]
 Antibacterials
  Tetracyclines
   Doxycycline
    D03903  Doxycycline calcium (USP)
 Dental and Oral Agents
  Doxycycline
   D03903  Doxycycline calcium (USP)
 Dermatological Agents
  Doxycycline
   D03903  Doxycycline calcium (USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor
    Tetracyclines
     Doxycycline
      D03903  Doxycycline calcium (USP)
BRITE hierarchy
Other DBs
CAS: 
94088-85-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        34
            1   Z   Ca   29.8200  -20.5939 #2+
            2   C8x C    12.1800  -20.0200
            3   C8x C    12.1800  -21.4200
            4   C8y C    13.3924  -22.1200
            5   C8y C    14.6049  -21.4200
            6   C8y C    14.6049  -20.0200
            7   C8x C    13.3924  -19.3200
            8   C5x C    15.8173  -22.1200
            9   C2y C    17.0297  -21.4200
            10  C1y C    17.0297  -20.0200
            11  C1y C    15.8173  -19.3200
            12  C2y C    18.2422  -22.1200
            13  C1z C    19.4546  -21.4200
            14  C1y C    19.4546  -20.0200
            15  C1y C    18.2422  -19.3200
            16  C5x C    20.6670  -22.1200
            17  C2y C    21.8795  -21.4200
            18  C2y C    21.8795  -20.0200
            19  C1y C    20.6670  -19.3200
            20  C5a C    23.1146  -22.1334
            21  N1a N    24.3219  -21.4366
            22  O5a O    23.1142  -23.5199
            23  O1a O    23.1146  -19.3066
            24  N1c N    20.6670  -17.9201
            25  C1a C    19.4418  -17.2126
            26  C1a C    21.8667  -17.2274
            27  O1a O    18.2422  -17.9203 #-
            28  C1a C    15.8173  -17.9200
            29  O1a O    13.3924  -23.5198 #-
            30  O5x O    15.8173  -23.5200
            31  O1a O    18.2422  -23.5197 #-
            32  O1a O    19.4546  -22.8200 #-
            33  O5x O    20.6670  -23.5199
            34  Z   Ca   29.8200  -20.5939 #2+
BOND        35
            1     2   3 1
            2     3   4 2
            3     4   5 1
            4     5   6 2
            5     6   7 1
            6     2   7 2
            7     5   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11    6  11 1
            12    9  12 2
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   10  15 1
            17   13  16 1
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   14  19 1
            22   17  20 1
            23   20  21 1
            24   20  22 2
            25   18  23 1
            26   19  24 1 #Down
            27   24  25 1
            28   24  26 1
            29   15  27 1 #Down
            30   11  28 1 #Down
            31    4  29 1
            32    8  30 2
            33   12  31 1
            34   13  32 1 #Down
            35   16  33 2
BRACKET     1    28.4200  -21.9100   28.4200  -18.9700
            1    32.2000  -18.9700   32.2000  -21.9100
            1  2
 ORIGINAL  1    1
 REPEAT    1   36

» Japanese version   » Back

DBGET integrated database retrieval system