KEGG   DRUG: D03917Help
Entry
D03917                      Drug                                   

Name
Drospirenone (JAN/USP/INN)
Formula
C24H30O3
Exact mass
366.2195
Mol weight
366.4932
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Aldosterone antagonist
Comment
Component of Angeliq (TN)
Target
mineralocorticoid receptor antagonist [HSA:4306] [KO:K08555]
  Pathway
hsa04960  Aldosterone-regulated sodium reabsorption  
 
Interaction
Drug interaction
Structure map
Glucocorticoid and meneralocorticoid receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    mineralocorticoid receptor
     Drospirenone
      D03917  Drospirenone (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
67392-87-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C1z C    25.7600  -21.4200
            2   C1z C    24.5000  -22.1200
            3   C1y C    26.8800  -22.1200
            4   O7x O    26.8800  -20.6500
            5   C1x C    24.6400  -20.6500
            6   C1y C    24.5000  -23.4500
            7   C1x C    23.3800  -21.4200
            8   C1a C    23.8700  -20.5800
            9   C1y C    26.8800  -23.4500
            10  C7x C    26.4600  -19.3200
            11  C1x C    25.0600  -19.3200
            12  C1y C    23.3800  -24.1500
            13  C1x C    22.1900  -22.1200
            14  O6a O    27.2300  -18.2700
            15  C1y C    22.1900  -23.4500
            16  C1y C    23.3800  -25.5500
            17  C1z C    21.0000  -24.1500
            18  C1y C    22.1900  -26.1800
            19  C2y C    21.0000  -25.4800
            20  C1x C    19.8100  -23.4500
            21  C1a C    21.0000  -22.7500
            22  C2x C    19.8100  -26.1800
            23  C1x C    18.6200  -24.1500
            24  C5x C    18.6200  -25.4800
            25  O5x O    17.4300  -26.1800
            26  C1x C    28.0924  -22.8200
            27  C1x C    23.3800  -26.9500
BOND        33
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Up
            4     1   5 1 #Down
            5     2   6 1
            6     2   7 1
            7     2   8 1 #Up
            8     3   9 1
            9     4  10 1
            10    5  11 1
            11    6  12 1
            12    7  13 1
            13   10  14 2
            14   12  15 1
            15   12  16 1
            16   15  17 1
            17   16  18 1
            18   17  19 1
            19   17  20 1
            20   17  21 1 #Up
            21   19  22 2
            22   20  23 1
            23   22  24 1
            24   24  25 2
            25    6   9 1
            26   10  11 1
            27   13  15 1
            28   18  19 1
            29   23  24 1
            30    3  26 1 #Up
            31    9  26 1 #Up
            32   16  27 1 #Up
            33   18  27 1 #Up

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