KEGG   DRUG: D03937Help
Entry
D03937                      Drug                                   

Name
Ecopipam hydrochloride (USAN)
Formula
C19H20ClNO. HCl
Exact mass
349.1
Mol weight
350.2821
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of addiction disorders [selective dopamine receptor D1/D5 antagonist]
Target
dopamine D1-receptor antagonist [HSA:1812] [KO:K04144];
dopamine D5-receptor antagonist [HSA:1816] [KO:K05840]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D1-receptor
     Ecopipam
      D03937  Ecopipam hydrochloride (USAN)
    dopamine D5-receptor
     Ecopipam
      D03937  Ecopipam hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
190133-94-9
PubChem: 
LigandBox: 
KCF data Show

ATOM        23
            1   C1y C    41.0797  -23.6232
            2   N1y N    42.3245  -22.9985
            3   C1x C    43.5969  -23.5763
            4   C1x C    43.9343  -24.9217
            5   C1y C    40.7976  -25.0004
            6   C8y C    43.0932  -26.0401
            7   C8y C    41.6952  -26.0712
            8   C1x C    40.0346  -22.6962
            9   C1x C    38.7093  -23.1377
            10  C8y C    38.4273  -24.5150
            11  C8y C    39.4722  -25.4419
            12  C8x C    40.9967  -27.2809
            13  C8y C    41.6952  -28.4907
            14  C8y C    43.0921  -28.4907
            15  C8x C    43.7905  -27.2809
            16  O1a O    40.9816  -29.7271
            17  X   Cl   43.7950  -29.7078
            18  C8x C    37.1020  -24.9565
            19  C8x C    36.8217  -26.3251
            20  C8x C    37.8667  -27.2520
            21  C8x C    39.1921  -26.8105
            22  C1a C    42.3674  -21.5990
            23  X   Cl   47.9627  -25.0181
BOND        25
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     1   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12    5  11 1
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17   15   6 2
            18   13  16 1
            19   14  17 1
            20   10  18 2
            21   18  19 1
            22   19  20 2
            23   20  21 1
            24   11  21 2
            25    2  22 1

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