KEGG   DRUG: Edaglitazone sodiumHelp
Entry
D03941                      Drug                                   

Name
Edaglitazone sodium (USAN)
Formula
C24H19N2O4S2. Na
Exact mass
486.0684
Mol weight
486.5384
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antidiabetic agent
 DG01685  Insulin sensitizer
  DG01795  PPAR gamma agonist
   DG01683  Thiazolidinedione
Other
 DG01733  PPAR agonist
  DG01683  Thiazolidinedione
Activity
Antidiabetic, Peroxisome proliferator-activated receptor (PPAR) gamma agonist
Comment
Treatment of type 2 diabetes
Target
NR1C3 (PPARG) [HSA:5468] [KO:K08530]
  Pathway
PPAR signaling pathway
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    peroxisome proliferator-activated receptor (PPAR) gamma
     Edaglitazone
      D03941  Edaglitazone sodium (USAN)
BRITE hierarchy
Other DBs
CAS: 
369631-81-2
PubChem: 
LigandBox: 
KCF data Show

ATOM        33
            1   C1y C    33.8533  -21.0740
            2   C5x C    33.8533  -22.4863
            3   N1x N    35.1949  -22.9099 #-
            4   C5x C    36.0423  -21.7801
            5   S2x S    35.1949  -20.6503
            6   O5x O    37.4545  -21.7801
            7   O5x O    32.7234  -23.3336
            8   C1b C    32.6528  -20.3679
            9   C8y C    31.4524  -21.0740
            10  C8y C    30.2236  -20.3779
            11  C8y C    29.0770  -21.0939
            12  C8y C    29.0179  -22.5061
            13  C8x C    30.2466  -23.2023
            14  C8x C    31.4639  -22.4863
            15  O2a O    27.8172  -23.1725
            16  C1b C    26.6400  -22.4661
            17  C1b C    25.4050  -23.1515
            18  C8y C    24.1622  -22.4062
            19  C8y C    24.2037  -21.0036
            20  O2x O    22.8840  -20.5325
            21  C8y C    22.0282  -21.6419
            22  N5x N    22.8188  -22.7987
            23  C1a C    25.3532  -20.2184
            24  C8y C    20.6491  -21.6728
            25  C8x C    19.9003  -20.4412
            26  C8x C    18.4884  -20.4732
            27  C8x C    17.8101  -21.7118
            28  C8x C    18.5589  -22.9435
            29  C8x C    19.9708  -22.9116
            30  S2x S    29.8970  -19.0660
            31  C8x C    28.5484  -18.9713
            32  C8x C    28.0417  -20.2246
            33  Z   Na   36.1200  -24.2900 #+
BOND        36
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     4   6 2
            7     2   7 2
            8     8   1 1
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14   13  14 2
            15    9  14 1
            16   12  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 1
            23   21  22 2
            24   18  22 1
            25   19  23 1
            26   21  24 1
            27   24  25 2
            28   25  26 1
            29   26  27 2
            30   27  28 1
            31   28  29 2
            32   24  29 1
            33   10  30 1
            34   30  31 1
            35   31  32 2
            36   11  32 1

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