KEGG   DRUG: D03959Help
Entry
D03959                      Drug                                   

Name
Efalizumab (USAN/INN);
Raptiva (TN)
Activity
Treatment of transplant rejections;
Antipruritic [immunomodulator monoclonal antibody which decreases the activation, migration, and adhesion of T-cells]
Remark
ATC code: 
Comment
anti-CD11a monoclonal antibody
Target
CD11a [HSA:3683] [KO:K05718]
  Pathway
hsa04514  Cell adhesion molecules (CAMs)
hsa04650  Natural killer cell mediated cytotoxicity
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AA Selective immunosuppressants
     L04AA21 Efalizumab
      D03959  Efalizumab (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Others
  Cellular antigens
   CD11a
    Efalizumab
     D03959  Efalizumab (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
214745-43-4
PubChem: 
DrugBank: 

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