KEGG   DRUG: ElarofibanHelp
Entry
D03971                      Drug                                   

Name
Elarofiban (USAN)
Formula
C22H32N4O4. H2O
Exact mass
434.2529
Mol weight
434.5292
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01811  Fibrinogen receptor antagonist
Activity
Treatment of thrombotic disorders [platelet fibrinogen receptor [GPIIb/IIIa] antagonist]
Target
glycoprotein alphaIIb/beta3 (GPIIb/IIIa) receptor [HSA:3674 3690] [KO:K06476 K06493]
  Pathway
Focal adhesion
ECM-receptor interaction
Brite
Target-based classification of drugs [BR:br08310]
 Others
  Cell adhesion molecules (CAMs)
   glycoprotein alpha IIb/beta3 (GPIIb/IIIa) receptor
    Elarofiban
     D03971  Elarofiban (USAN)
BRITE hierarchy
Other DBs
CAS: 
221005-96-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        31
            1   C1x C     9.8000  -16.2400
            2   N1x N     9.8000  -17.6400
            3   C1x C    11.0124  -18.3400
            4   C1x C    12.2249  -17.6400
            5   C1y C    12.2249  -16.2400
            6   C1x C    11.0124  -15.5400
            7   C1b C    13.4560  -15.5290
            8   C1b C    14.6612  -16.2247
            9   C5a C    15.8435  -15.5419
            10  N1y N    17.0375  -16.2312
            11  O5a O    15.8435  -14.1402
            12  C1x C    17.0376  -17.6397
            13  C1x C    18.2501  -18.3396
            14  C1x C    19.4625  -17.6395
            15  C1y C    19.4623  -16.2309
            16  C1x C    18.2498  -15.5311
            17  C5a C    20.6690  -15.5341
            18  N1b N    21.8697  -16.2273
            19  O5a O    20.6689  -14.1401
            20  C1c C    23.0543  -15.5433
            21  C1b C    24.2470  -16.2320
            22  C6a C    25.4357  -15.5457
            23  C8y C    23.0544  -14.1402
            24  C8x C    24.2485  -13.4506
            25  N5x N    24.2484  -12.0506
            26  C8x C    23.0359  -11.3507
            27  C8x C    21.8417  -12.0403
            28  C8x C    21.8419  -13.4403
            29  O6a O    26.6263  -16.2332
            30  O6a O    25.4358  -14.1402
            31  O0  O    24.2900  -19.0400
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    9  11 2
            12   10  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   10  16 1
            18   15  17 1 #Down
            19   17  18 1
            20   17  19 2
            21   18  20 1
            22   20  21 1
            23   21  22 1
            24   20  23 1 #Down
            25   23  24 2
            26   24  25 1
            27   25  26 2
            28   26  27 1
            29   27  28 2
            30   23  28 1
            31   22  29 1
            32   22  30 2

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