KEGG   DRUG: D04006Help
Entry
D04006                      Drug                                   

Name
Enprofylline (USAN/INN)
Formula
C8H10N4O2
Exact mass
194.0804
Mol weight
194.1906
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator [DS:H00079]
Comment
xanthines
Target
adenosine A1 receptor antagonist [HSA:134] [KO:K04265];
adenosine A2a receptor antagonist [HSA:135] [KO:K04266];
adenosine A2b receptor antagonist [HSA:136] [KO:K04267]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adenosine
    adenosine A1 receptor
     Enprofylline
      D04006  Enprofylline (USAN/INN)
    adenosine A2a receptor
     Enprofylline
      D04006  Enprofylline (USAN/INN)
    adenosine A2b receptor
     Enprofylline
      D04006  Enprofylline (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
41078-02-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   N4x N    14.2100  -16.5200
            2   C8y C    14.2100  -17.9200
            3   N4y N    13.0200  -18.6200
            4   C8y C    11.7600  -17.9200
            5   C8y C    11.7600  -16.5200
            6   C8y C    13.0200  -15.8200
            7   O5x O    13.0200  -14.4200
            8   O5x O    15.4000  -18.6200
            9   N5x N    10.4300  -18.3400
            10  C8x C     9.6600  -17.2200
            11  N4x N    10.4300  -16.1000
            12  C1b C    13.0200  -20.0200
            13  C1b C    11.8300  -20.7200
            14  C1a C    11.8300  -22.1200
BOND        15
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     6   7 2
            8     2   8 2
            9     4   9 1
            10    9  10 2
            11   10  11 1
            12    5  11 1
            13    3  12 1
            14   12  13 1
            15   13  14 1

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