KEGG   DRUG: D04079Help
Entry
D04079                      Drug                                   

Name
Ethacrynate sodium (USP)
Product
Formula
C13H11Cl2O4. Na
Exact mass
323.9932
Mol weight
325.1198
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Diuretic
Remark
ATC code: 
Drug group: 
Comment
Component of Edecrin (TN)
Target
Na-K-Cl cotransporter 1 inhibitor [HSA:6557] [KO:K14425];
Na-K-Cl cotransporter 2 inhibitor [HSA:6558] [KO:K10951]
Interaction
Drug interaction
Structure map
Ion transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C03 DIURETICS
   C03C HIGH-CEILING DIURETICS
    C03CC Aryloxyacetic acid derivatives
     C03CC01 Etacrynic acid
      D04079  Ethacrynate sodium (USP)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Diuretics, Loop
   Ethacrynate/Ethacrynic Acid
    D04079  Ethacrynate sodium (USP)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A1
     Etacrynic acid
      D04079  Ethacrynate sodium (USP)
BRITE hierarchy
Other DBs
CAS: 
6500-81-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   C8y C    33.3355  -14.6714
            2   C8y C    32.1238  -13.9723
            3   C5a C    34.5530  -13.9723
            4   C8x C    33.3355  -16.0694
            5   C8y C    30.9064  -14.6714
            6   X   Cl   32.1297  -12.5743
            7   C2c C    35.7645  -14.6714
            8   O5a O    34.5530  -12.5743
            9   C8x C    32.1238  -16.7742
            10  C8y C    30.9064  -16.0694
            11  X   Cl   29.6948  -13.9723
            12  C1b C    36.9703  -13.9783
            13  C2a C    35.7645  -16.0751
            14  O2a O    29.6948  -16.7742
            15  C1a C    38.1819  -14.6773
            16  C1b C    28.4833  -16.0751
            17  C6a C    27.2775  -16.7801
            18  O6a O    26.0600  -16.0751 #-
            19  O6a O    27.2775  -18.1781
            20  Z   Na   24.0799  -16.0299 #+
BOND        19
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 2
            8     4   9 2
            9     5  10 2
            10    5  11 1
            11    7  12 1
            12    7  13 2
            13   10  14 1
            14   12  15 1
            15   14  16 1
            16   16  17 1
            17   17  18 1
            18   17  19 2
            19    9  10 1

» Japanese version   » Back

DBGET integrated database retrieval system