KEGG   DRUG: D04087Help
Entry
D04087                      Drug                                   

Name
Ethybenztropine (USAN);
Etybenzatropine (INN);
Panolid (TN)
Formula
C22H27NO
Exact mass
321.2093
Mol weight
321.4559
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic, Antiparkinsonian
Remark
ATC code: 
Drug group: 
Comment
Atropine [CPD:C01479] derivative
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AC Ethers of tropine or tropine derivatives
     N04AC30 Etybenzatropine
      D04087  Ethybenztropine (USAN); Etybenzatropine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Etybenzatropine
      D04087  Ethybenztropine (USAN); Etybenzatropine (INN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D04087  Ethybenztropine (USAN); Etybenzatropine (INN)
BRITE hierarchy
Other DBs
CAS: 
524-83-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C1x C    11.5738  -12.2308
            2   C1x C    11.9019  -11.0591
            3   C1y C    12.7455  -11.9496
            4   C1y C    13.0736  -10.7779
            5   N1y N    11.8082   -9.4656
            6   C1x C    14.6202  -11.9496
            7   C1x C    14.3390  -10.7779
            8   C1y C    15.6513  -12.5120
            9   O2a O    16.7293  -13.4025
            10  C1c C    17.9479  -13.4025
            11  C8y C    18.5572  -12.3245
            12  C8y C    18.5572  -14.5273
            13  C1b C    11.0591   -8.2814
            14  C1a C     9.6591   -8.2814
            15  C8x C    19.9500  -12.3117
            16  C8x C    20.6388  -11.0929
            17  C8x C    19.9277   -9.8870
            18  C8x C    18.5350   -9.8997
            19  C8x C    17.8461  -11.1185
            20  C8x C    17.8078  -15.7471
            21  C8x C    18.4744  -16.9782
            22  C8x C    19.8739  -17.0164
            23  C8x C    20.6233  -15.7967
            24  C8x C    19.9567  -14.5656
BOND        27
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   10  12 1
            12    4   5 1
            13    7   8 1
            14    5  13 1
            15   13  14 1
            16   11  15 2
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   18  19 2
            21   11  19 1
            22   12  20 2
            23   20  21 1
            24   21  22 2
            25   22  23 1
            26   23  24 2
            27   12  24 1

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