KEGG   DRUG: Fenfluramine hydrochlorideHelp
Entry
D04148                      Drug                                   

Name
Fenfluramine hydrochloride (USAN);
Pondimin (TN)
Formula
C12H16F3N. HCl
Exact mass
267.1002
Mol weight
267.7183
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Other
 DG01706  Antiobesity
  DG01705  Anoretic
   DG01704  Phenethylamine anorexic
Remark
ATC code: A08AA02
Chemical structure group: DG00103
Efficacy
Appetite suppressant
Target
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
HTR2 [HSA:3356 3357 3358] [KO:K04157]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
   A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
    A08AA Centrally acting antiobesity products
     A08AA02 Fenfluramine
      D04148  Fenfluramine hydrochloride (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    HTR2
     D04148  Fenfluramine hydrochloride (USAN)
 Transporters
  Solute carrier family
   SLC6
    SLC6A4 (HTT)
     D04148  Fenfluramine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 404-82-0
PubChem: 47206095
ChEBI: 59729
ChEMBL: CHEMBL2106217
DrugBank: DB00574
LigandBox: D04148
NIKKAJI: J349.650C
KCF data Show

ATOM        17
            1   C8y C    16.3100  -16.0300
            2   C8x C    15.1200  -15.3300
            3   C8x C    16.3100  -17.4300
            4   C1b C    17.5000  -15.3300
            5   C8y C    13.8600  -16.0300
            6   C8x C    15.1200  -18.1300
            7   C1c C    18.7600  -16.0300
            8   C8x C    13.8600  -17.4300
            9   C1d C    12.6700  -15.3300
            10  N1b N    19.9500  -15.3300
            11  C1a C    18.7600  -17.4300
            12  X   F    11.3400  -14.5600
            13  X   F    12.0400  -16.3800
            14  X   F    13.4400  -14.2100
            15  C1b C    21.2100  -16.0300
            16  C1a C    22.4000  -15.3300
            17  X   Cl   23.3100  -17.7800
BOND        16
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     5   9 1
            9     7  10 1
            10    7  11 1
            11    9  12 1
            12    9  13 1
            13    9  14 1
            14   10  15 1
            15   15  16 1
            16    6   8 1

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