KEGG   DRUG: D04155Help
Entry
D04155                      Drug                                   

Name
Fenobam (USAN)
Formula
C11H11ClN4O2. H2O
Exact mass
284.0676
Mol weight
284.6989
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Sedative-hypnotic
Target
metabotropic glutamate receptor 5 (mGluR5) antagonist [HSA:2915] [KO:K04604]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04720  Long-term potentiation
hsa04724  Glutamatergic synapse
hsa04730  Long-term depression  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Metabotropic glutamate receptor family
   Glutamate (metabotropic)
    metabotropic glutamate receptor 5 (mGluR5)
     Fenobam
      D04155  Fenobam (USAN)
BRITE hierarchy
Other DBs
CAS: 
63540-28-3
PubChem: 
LigandBox: 
KCF data Show

ATOM        19
            1   C8y C    24.4346  -14.7718
            2   C8x C    24.4346  -16.1715
            3   C8x C    25.6467  -16.8713
            4   C8x C    26.8588  -16.1715
            5   C8y C    26.8588  -14.7718
            6   C8x C    25.6467  -14.0721
            7   N1b N    28.0896  -14.0611
            8   C5a C    29.2944  -14.7565
            9   N1b N    30.4764  -14.0740
            10  O5a O    29.2948  -16.1711
            11  C2y C    31.6700  -14.7630
            12  N1y N    31.6623  -16.1716
            13  C1x C    32.9962  -16.6136
            14  C5x C    33.8287  -15.4817
            15  N2x N    33.0094  -14.3400
            16  O5x O    35.2134  -15.4901
            17  C1a C    30.4988  -17.0070
            18  X   Cl   23.2315  -14.0772
            19  O0  O    38.1688  -15.4799
BOND        19
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    8  10 2
            11    9  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   11  15 2
            17   14  16 2
            18   12  17 1
            19    1  18 1

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