KEGG   DRUG: Fiduxosin hydrochlorideHelp
Entry
D04184                      Drug                                   

Name
Fiduxosin hydrochloride (USAN)
Formula
C30H29N5O4S. HCl
Exact mass
591.1707
Mol weight
592.1083
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01465  alpha-Adrenergic receptor antagonist
   DG01457  alpha1-Adrenergic receptor antagonist
Activity
Treatment of benign prostatic hyperplasia [alpha1a-adrenoceptor antagonist]
Target
ADRA1A [HSA:148] [KO:K04135]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Salivary secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1a-adrenergic receptor
     Fiduxosin
      D04184  Fiduxosin hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
208992-74-9
PubChem: 
ChEMBL: 
LigandBox: 
KCF data Show

ATOM        41
            1   C8x C     5.3703   -2.9865
            2   C8y C     5.3703   -4.3849
            3   N5x N     6.5589   -5.0840
            4   C8y C     7.8173   -4.3849
            5   C8y C     7.8173   -2.9865
            6   N5x N     6.5589   -2.2874
            7   C8y C     9.1458   -4.8043
            8   C8y C     9.9148   -3.6857
            9   S2x S     9.1458   -2.5670
            10  C8y C    11.3132   -3.6857
            11  N4y N    12.0124   -4.8743
            12  C8y C    11.3132   -6.0629
            13  N4x N     9.9148   -6.0629
            14  C8y C     4.1588   -5.0778
            15  C8x C     2.9424   -4.3687
            16  C8x C     1.7270   -5.0636
            17  C8x C     1.7211   -6.4636
            18  C8x C     2.9376   -7.1727
            19  C8x C     4.1529   -6.4778
            20  O5x O    12.0044   -2.4777
            21  O5x O    12.0263   -7.3102
            22  C1b C    13.4124   -4.8743
            23  C1b C    14.1302   -6.1181
            24  C1b C    15.5397   -6.1185
            25  C1b C    16.2271   -7.3098
            26  N1y N    17.6397   -7.3104
            27  C1x C    18.4479   -8.4234
            28  C1y C    19.7562   -7.9986
            29  C1y C    19.7565   -6.6231
            30  C1x C    18.4484   -6.1978
            31  C1x C    20.9684   -8.6988
            32  O2x O    22.1810   -7.9991
            33  C8y C    22.1813   -6.6236
            34  C8y C    20.9690   -5.9234
            35  C8x C    23.3939   -5.9239
            36  C8x C    23.3942   -4.5239
            37  C8x C    22.1819   -3.8236
            38  C8y C    20.9693   -4.5234
            39  O2a O    19.7915   -3.8433
            40  C1a C    18.5901   -4.5369
            41  X   Cl    7.2800   -8.0500
BOND        46
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    5   9 1
            11    8  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 1
            15   13   7 1
            16    2  14 1
            17   14  15 2
            18   15  16 1
            19   16  17 2
            20   17  18 1
            21   18  19 2
            22   14  19 1
            23   10  20 2
            24   12  21 2
            25   11  22 1
            26   22  23 1
            27   23  24 1
            28   24  25 1
            29   25  26 1
            30   26  27 1
            31   27  28 1
            32   28  29 1
            33   29  30 1
            34   26  30 1
            35   28  31 1
            36   31  32 1
            37   32  33 1
            38   33  34 1
            39   29  34 1
            40   33  35 2
            41   35  36 1
            42   36  37 2
            43   37  38 1
            44   34  38 2
            45   38  39 1
            46   39  40 1

» Japanese version   » Back

DBGET integrated database retrieval system