KEGG   DRUG: Flestolol sulfateHelp
Entry
D04190                      Drug                                   

Name
Flestolol sulfate (USAN)
Formula
C15H22FN3O4. H2SO4
Exact mass
425.1268
Mol weight
425.4298
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Activity
Antiarrhythmic, beta-Adrenergic receptor antagonist
Target
ADRB1 [HSA:153] [KO:K04141];
ADRB2 [HSA:154] [KO:K04142];
ADRB3 [HSA:155] [KO:K04143]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Flestolol
      D04190  Flestolol sulfate (USAN)
    beta2-adrenergic receptor
     Flestolol
      D04190  Flestolol sulfate (USAN)
    beta3-adrenergic receptor
     Flestolol
      D04190  Flestolol sulfate (USAN)
BRITE hierarchy
Other DBs
CAS: 
88844-73-9
PubChem: 
LigandBox: 
KCF data Show

ATOM        28
            1   C8x C     3.6400   -5.2500
            2   C8x C     3.6400   -6.6500
            3   C8x C     4.8524   -7.3500
            4   C8x C     6.0649   -6.6500
            5   C8y C     6.0649   -5.2500
            6   C8y C     4.8524   -4.5500
            7   C7a C     7.2960   -4.5390
            8   X   F     4.8524   -3.1502
            9   O7a O     8.5012   -5.2347
            10  O6a O     7.2957   -3.1501
            11  C1b C     9.6835   -4.5519
            12  C1c C    10.8775   -5.2412
            13  C1b C    12.0654   -4.5552
            14  O1a O    10.8777   -6.6497
            15  N1b N    13.2565   -5.2429
            16  C1d C    14.4459   -4.5561
            17  C1b C    15.6362   -5.2434
            18  C1a C    15.4359   -3.5661
            19  C1a C    13.4560   -3.5661
            20  N1b N    16.8261   -4.5563
            21  C5a C    18.0162   -5.2435
            22  N1a N    19.2061   -4.5564
            23  O5a O    18.0163   -6.6498
            24  S4a S    24.6079   -5.0160
            25  O1d O    26.0076   -5.0160
            26  O1d O    23.2080   -5.0558
            27  O1d O    24.6707   -6.4157
            28  O1d O    24.6114   -3.6161
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     6   8 1
            9     7   9 1
            10    7  10 2
            11    9  11 1
            12   11  12 1
            13   12  13 1
            14   12  14 1
            15   13  15 1
            16   15  16 1
            17   16  17 1
            18   16  18 1
            19   16  19 1
            20   17  20 1
            21   20  21 1
            22   21  22 1
            23   21  23 2
            24   24  25 1
            25   24  26 1
            26   24  27 2
            27   24  28 2

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