KEGG   DRUG: D04226Help
Entry
D04226                      Drug                                   

Name
Flupirtine maleate (USAN)
Formula
C15H17FN4O2. C4H4O4
Exact mass
420.1445
Mol weight
420.3916
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Analgesic
Remark
ATC code: 
Drug group: 
Target
N-methyl-D-aspartate receptor antagonist [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02B OTHER ANALGESICS AND ANTIPYRETICS
    N02BG Other analgesics and antipyretics
     N02BG07 Flupirtine
      D04226  Flupirtine maleate (USAN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Flupirtine
      D04226  Flupirtine maleate (USAN)
BRITE hierarchy
Other DBs
CAS: 
75507-68-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   C8y C    16.4929   -5.8472
            2   C8x C    16.4929   -7.2504
            3   C8x C    17.7081   -7.9520
            4   C8y C    18.9234   -7.2504
            5   C8y C    18.9234   -5.8472
            6   N5x N    17.7081   -5.1456
            7   N1b N    15.2778   -5.1456
            8   N1a N    20.1573   -5.1345
            9   N1b N    20.1573   -7.9630
            10  C1b C    14.0795   -5.8375
            11  C7a C    21.3652   -7.2657
            12  C8y C    12.8894   -5.1505
            13  C8x C    12.8893   -3.7426
            14  C8x C    11.6740   -3.0411
            15  C8y C    10.4589   -3.7428
            16  C8x C    10.4591   -5.1507
            17  C8x C    11.6743   -5.8522
            18  X   F     9.2436   -3.0414
            19  O7a O    22.5503   -7.9501
            20  O6a O    21.3656   -5.8476
            21  C1b C    23.7470   -7.2592
            22  C1a C    24.9376   -7.9468
            23  C2b C    32.1099   -4.6926
            24  C2b C    30.4361   -4.6926
            25  C6a C    32.7375   -5.8781
            26  C6a C    29.8085   -5.8781
            27  O6a O    32.1099   -6.9939
            28  O6a O    34.1321   -5.8781
            29  O6a O    28.4138   -5.8781
            30  O6a O    30.4361   -6.9939
BOND        30
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     5   8 1
            9     4   9 1
            10    7  10 1
            11    9  11 1
            12   10  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17   16  17 2
            18   12  17 1
            19   15  18 1
            20   11  19 1
            21   11  20 2
            22   19  21 1
            23   21  22 1
            24   23  24 2
            25   23  25 1
            26   24  26 1
            27   25  27 1
            28   25  28 2
            29   26  29 1
            30   26  30 2

» Japanese version   » Back

DBGET integrated database retrieval system