KEGG   DRUG: Flupirtine maleateHelp
Entry
D04226                      Drug                                   

Name
Flupirtine maleate (USAN)
Formula
C15H17FN4O2. C4H4O4
Exact mass
420.1445
Mol weight
420.3916
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01498  NMDA receptor antagonist
Remark
ATC code: 
Chemical group: 
Activity
Analgesic, Antipyretic
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Glutamatergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02B OTHER ANALGESICS AND ANTIPYRETICS
    N02BG Other analgesics and antipyretics
     N02BG07 Flupirtine
      D04226  Flupirtine maleate (USAN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Flupirtine
      D04226  Flupirtine maleate (USAN)
BRITE hierarchy
Other DBs
CAS: 
75507-68-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   C8y C    16.4929   -5.8472
            2   C8x C    16.4929   -7.2504
            3   C8x C    17.7081   -7.9520
            4   C8y C    18.9234   -7.2504
            5   C8y C    18.9234   -5.8472
            6   N5x N    17.7081   -5.1456
            7   N1b N    15.2778   -5.1456
            8   N1a N    20.1573   -5.1345
            9   N1b N    20.1573   -7.9630
            10  C1b C    14.0795   -5.8375
            11  C7a C    21.3652   -7.2657
            12  C8y C    12.8894   -5.1505
            13  C8x C    12.8893   -3.7426
            14  C8x C    11.6740   -3.0411
            15  C8y C    10.4589   -3.7428
            16  C8x C    10.4591   -5.1507
            17  C8x C    11.6743   -5.8522
            18  X   F     9.2436   -3.0414
            19  O7a O    22.5503   -7.9501
            20  O6a O    21.3656   -5.8476
            21  C1b C    23.7470   -7.2592
            22  C1a C    24.9376   -7.9468
            23  C2b C    32.1099   -4.6926
            24  C2b C    30.4361   -4.6926
            25  C6a C    32.7375   -5.8781
            26  C6a C    29.8085   -5.8781
            27  O6a O    32.1099   -6.9939
            28  O6a O    34.1321   -5.8781
            29  O6a O    28.4138   -5.8781
            30  O6a O    30.4361   -6.9939
BOND        30
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     5   8 1
            9     4   9 1
            10    7  10 1
            11    9  11 1
            12   10  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17   16  17 2
            18   12  17 1
            19   15  18 1
            20   11  19 1
            21   11  20 2
            22   19  21 1
            23   21  22 1
            24   23  24 2
            25   23  25 1
            26   24  26 1
            27   25  27 1
            28   25  28 2
            29   26  29 1
            30   26  30 2

» Japanese version   » Back

DBGET integrated database retrieval system