KEGG   DRUG: Ganciclovir sodiumHelp
Entry
D04301                      Drug                                   

Name
Ganciclovir sodium (USAN);
Cytovene IV (TN)
Product
  Generic
Formula
C9H12N5O4. Na
Exact mass
277.0787
Mol weight
277.2124
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antiviral
 DG01937  Anti-cytomegalovirus agent
Remark
ATC code: 
Chemical group: 
Activity
Antiviral, DNA polymerase inhibitor
  Disease
CMV retinitis [DS:H00368]
Comment
Acyclovir type
Target
DNA polymerase
Metabolism
Transporter: SLC22A1 [HSA:6580]
Interaction
Drug interaction
Structure map
Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB06 Ganciclovir
      D04301  Ganciclovir sodium (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD09 Ganciclovir
      D04301  Ganciclovir sodium (USAN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-cytomegalovirus (CMV) Agents
   Ganciclovir
    D04301  Ganciclovir sodium (USAN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-CMV agents
   DNA polymerase inhibitor
    Purine analogue
     Ganciclovir
      D04301  Ganciclovir sodium (USAN)
Cytochrome P450 interactions [BR:br08309]
 Transporter substrates
  OAT1
   Ganciclovir
    D04301  Ganciclovir sodium (USAN)
  OAT3
   Ganciclovir
    D04301  Ganciclovir sodium (USAN)
  SLC22A1
   Ganciclovir
    D04301  Ganciclovir sodium (USAN)
Antivirals [br08351.html]
 D04301
BRITE hierarchy
Other DBs
CAS: 
107910-75-8
PubChem: 
ChEMBL: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   N4y N    17.7005  -17.0904
            2   C8y C    18.9563  -16.6020
            3   C8y C    18.9563  -15.2067
            4   N5x N    17.6307  -14.8578
            5   C8x C    16.8633  -15.9741
            6   N5x N    20.3516  -17.2997
            7   C8y C    21.3981  -16.5322
            8   N5x N    21.3981  -15.1369
            9   C8y C    20.1423  -14.5090
            10  O1a O    20.1423  -13.1137 #-
            11  N1a N    22.6539  -17.2299
            12  C1b C    17.7005  -18.5554
            13  O2a O    16.5145  -19.2531
            14  C1c C    15.2587  -18.5554
            15  C1b C    14.1424  -19.2531
            16  C1b C    15.2587  -17.0904
            17  O1a O    14.0726  -16.3927
            18  O1a O    12.8866  -18.5554
            19  Z   Na   21.9480  -12.8288 #+
BOND        19
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     1   5 1
            6     2   6 1
            7     6   7 2
            8     7   8 1
            9     8   9 2
            10    3   9 1
            11    9  10 1
            12    7  11 1
            13    1  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   14  16 1
            18   16  17 1
            19   15  18 1

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