KEGG   DRUG: D04479Help
Entry
D04479                      Drug                                   

Name
Hyoscyamine hydrobromide (USP)
Formula
C17H23NO3. HBr
Exact mass
369.094
Mol weight
370.2814
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic
Remark
ATC code: 
Drug group: 
Comment
Component of Pyridium plus (TN)
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03B BELLADONNA AND DERIVATIVES, PLAIN
    A03BA Belladonna alkaloids, tertiary amines
     A03BA03 Hyoscyamine
      D04479  Hyoscyamine hydrobromide (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Hyoscyamine
      D04479  Hyoscyamine hydrobromide (USP)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D04479  Hyoscyamine hydrobromide (USP)
BRITE hierarchy
Other DBs
CAS: 
306-03-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C1x C    20.5572  -18.9601
            2   C1x C    20.8747  -17.7725
            3   C1y C    21.7506  -18.6484
            4   C1y C    22.0622  -17.4551
            5   N1y N    20.8218  -16.1559
            6   C1x C    23.6201  -18.6542
            7   C1x C    23.3614  -17.4609
            8   C1a C    20.7695  -14.7862
            9   C1y C    24.6429  -19.2010
            10  O7a O    25.6951  -20.1239
            11  C7a C    26.9238  -20.1181
            12  C1c C    27.5293  -19.0482
            13  O6a O    27.5116  -21.1939
            14  C8y C    28.7697  -19.0422
            15  C1b C    26.9120  -17.9841
            16  C8x C    29.3868  -20.1122
            17  C8x C    29.3752  -17.9723
            18  O1a O    27.5234  -16.9143
            19  C8x C    30.6214  -20.1064
            20  C8x C    30.6037  -17.9665
            21  C8x C    31.2269  -19.0364
            22  X   Br   34.0900  -19.1100
BOND        23
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     6   9 1
            9     9  10 1 #Down
            10   10  11 1
            11   11  12 1
            12   11  13 2
            13   12  14 1
            14   12  15 1 #Down
            15   14  16 2
            16   14  17 1
            17   15  18 1
            18   16  19 1
            19   17  20 2
            20   19  21 2
            21    4   5 1
            22    7   9 1
            23   20  21 1

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