KEGG   DRUG: D04539Help
Entry
D04539                      Drug                                   

Name
Insulin detemir (genetical recombination) (JAN);
Insulin detemir (USAN/INN);
Levemir (TN)
Product
Formula
C267H402N64O76S6
Exact mass
5912.7883
Mol weight
5916.822
Sequence
(A chain) Gly Ile Val Glu Gln Cys Cys Thr Ser Ile Cys Ser Leu Tyr
Gln Leu Glu Asn Tyr Cys Asn (Disulfide bridge: 6-11)
(B chain) Phe Val Asn Gln His Leu Cys Gly Ser His Leu Val Glu Ala
Leu Tyr Leu Val Cys Gly Glu Arg Gly Phe Phe Tyr Thr Pro
Lys-C14H27O (Disulfide bridge: A7-B7; A20-B19)
  Type
Peptide
Activity
Antidiabetic [DS:H00408 H00409]
Remark
Therapeutic category: 
ATC code: 
Target
insulin receptor agonist [HSA:3643] [KO:K04527]
  Pathway
hsa04910  Insulin signaling pathway
hsa04930  Type II diabetes mellitus  
 
Interaction
CYP induction: CYP1A2 [HSA:1544]
Drug interaction
Structure map
Antidiabetics
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2492  Pancreatic hormones
     D04539  Insulin detemir (genetical recombination) (JAN); Insulin detemir (USAN/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10A INSULINS AND ANALOGUES
    A10AE Insulins and analogues for injection, long-acting
     A10AE05 Insulin detemir
      D04539  Insulin detemir (genetical recombination) (JAN); Insulin detemir (USAN/INN)
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Insulins
   Insulin detemir
    D04539  Insulin detemir (genetical recombination) (JAN); Insulin detemir (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Receptor tyrosine kinase
   RTK class II (Insulin receptor family)
    insulin receptor [HSA:3643] [KO:K04527]
     Insulin detemir [ATC:A10AE05]
      D04539  Insulin detemir (genetical recombination) (JAN); Insulin detemir (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
169148-63-4
PubChem: 
NIKKAJI: 

» Japanese version   » Back

DBGET integrated database retrieval system