KEGG   DRUG: D04541Help
Entry
D04541            Mixture   Drug                                   

Name
Insulin human, isophane (USP)
Component
Insulin human [DR:D03230], Isophane insulin [DR:D04547]
Activity
Antidiabetic [DS:H00408 H00409]
Remark
Drug group: 
Comment
Component of Humulin 70/30 (TN)
Target
insulin receptor agonist [HSA:3643] [KO:K04527]
  Pathway
hsa04520  Adherens junction
hsa04910  Insulin signaling pathway
hsa04930  Type II diabetes mellitus
hsa04960  Aldosterone-regulated sodium reabsorption  
 
Interaction
CYP induction: CYP1A2 [HSA:1544]
Drug interaction
Structure map
Antidiabetics
Brite
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Insulins
   Isophane insulin (human)
    D04541  Insulin human, isophane (USP)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Receptor tyrosine kinase
   RTK class II (Insulin receptor family)
    insulin receptor
     Insulin (human)
      D04541  Insulin human, isophane (USP)
Cytochrome P450 interactions [BR:br08309]
 Inducers
  CYP1A2
   Insulin
    D04541  Insulin human, isophane (USP)
BRITE hierarchy
Other DBs
PubChem: 

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