KEGG   DRUG: Insulin, isophane
Entry
D04547                      Drug                                   
Name
Insulin, isophane (USP);
Isophane insulin human (genetical recombination) injectable aqueous suspension (JP18);
Isophane insulin (aqueous suspension) (JAN);
Humalog PEN (TN)
Class
Antidiabetic agent
 DG01636  Insulin preparation
  DG01802  Human insulin
Metabolizing enzyme inducer
 DG01637  CYP1A2 inducer
Remark
Therapeutic category: 2492
Product: D04547<JP>
Efficacy
Antidiabetic, Insulin receptor agonist
Target
INSR (CD220) [HSA:3643] [KO:K04527]
  Pathway
hsa04910  Insulin signaling pathway
Interaction
CYP induction: CYP1A2 [HSA:1544]
Structure map
map07051  Antidiabetics
Brite
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Insulins
   Insulin, Intermediate-acting
    Isophane Insulin, Human
     D04547  Insulin, isophane (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2492  Pancreatic hormones
     D04547  Insulin, isophane (USP); Isophane insulin human (genetical recombination) injectable aqueous suspension (JP18); Isophane insulin (aqueous suspension) (JAN)
Drug groups [BR:br08330]
 Antidiabetic agent
  DG01636  Insulin preparation
   DG01802  Human insulin
    D04547  Insulin, isophane
 Metabolizing enzyme inducer
  DG01637  CYP1A2 inducer
   D04547  Insulin, isophane
Drug classes [BR:br08332]
 Antidiabetic agent
  DG01636  Insulin preparation
   D04547  Insulin, isophane
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Receptor tyrosine kinases (RTK)
   INSR family
    INSR (CD220)
     D04547  Insulin, isophane (USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D04547  Isophane insulin human (genetical recombination) injectable aqueous suspension
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D04547
Other DBs
CAS: 53027-39-7
PubChem: 17398129

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Ontology (7)   
   KEGG BRITE (7)   
Pathway (1)   
   KEGG PATHWAY (1)   
Drug (2)   
   KEGG DGROUP (2)   
Chemical substance (1)   
   PubChem (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (13)   

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