KEGG   DRUG: D04695Help
Entry
D04695                      Drug                                   
Name
Leridistim (USAN/INN)
Formula
C1550H2463N425O462S12
Exact mass
34806.8949
Mol weight
34828.4915
Sequence
ANCSNMIDEI ITHLKQPPLP LLDFNNLNGE DQDILMDNNL RRPNLEAFNR AVKSLQNASA
IESILKNLLP CLPLATAAPT RHPIHIKDGD WNEFRRKLTF YLKTLENAQA QQYVEGGGGS
PGEPSGPIST INPSPPSKES HKSPNMATPL GPASSLPQSF LLKSLEQVRK IQGDGAALQE
KLCATYKLCH PEELVLLGHS LGIPWAPLSS CPSQALQLAG CLSQLHSGLF LYQGLLQALE
GISPELGPTL DTLQLDVADF ATTIWQQMEE LGMAPALQPT QGAMPAFASA FQRRAGGVLV
ASHLQSFLEV SYRVLRHLAQ P
  Type
Peptide
Activity
Treatment of chemotherapy-induced neutropenia and thrombocytopenia [multifunctional agonist that activates both interleukin-3 and G-CSF receptors]
Target
granulocyte colony stimulating factor (G-CSF) receptor agonist [HSA:1441] [KO:K05061];
interleukin-3 (IL-3) receptor agonist [HSA:3563] [KO:K04737]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04210  Apoptosis
hsa04630  Jak-STAT signaling pathway  
 
Brite
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class I cytokine receptors (hematopoietin family receptors)
   interleukin 3 receptor [HSA:3563] [KO:K04737]
    Leridistim
     D04695  Leridistim (USAN/INN)
   granulocyte colony stimulating factor (G-CSF) receptor [HSA:1441] [KO:K05061]
    Leridistim
     D04695  Leridistim (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
193700-51-5
PubChem: 

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