KEGG   DRUG: D04708Help
Entry
D04708                      Drug                                   

Name
Levdobutamine lactobionate (USAN)
Formula
C12H22O12. C18H23NO3
Exact mass
659.2789
Mol weight
659.676
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Cardiotonic
Remark
Drug group: 
Comment
The target of Levdobutamine is beta1-adrenargic receptor.
Target
beta1-adrenergic receptor agonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Levdobutamine
      D04708  Levdobutamine lactobionate (USAN)
BRITE hierarchy
Other DBs
CAS: 
129388-07-4
PubChem: 
LigandBox: 
KCF data Show

ATOM        46
            1   C8y C    27.7415  -15.2344
            2   C8x C    28.9566  -14.5425
            3   C8x C    27.7358  -16.6357
            4   C1b C    26.5321  -14.5366
            5   C8y C    30.2361  -15.2460
            6   C8x C    28.9449  -17.3392
            7   C1b C    25.3169  -15.2344
            8   C8y C    30.2301  -16.6415
            9   O1a O    31.3813  -14.5542
            10  N1b N    24.1076  -14.5425
            11  O1a O    31.4395  -17.3449
            12  C1c C    22.9040  -15.2403
            13  C1b C    21.6888  -14.5425
            14  C1a C    22.9040  -16.6357
            15  C1b C    20.4793  -15.2403
            16  C8y C    19.2642  -14.5425
            17  C8x C    18.0607  -15.2403
            18  C8x C    19.2642  -13.1471
            19  C8x C    16.8454  -14.5425
            20  C8x C    18.0607  -12.4435
            21  C8y C    16.8454  -13.1471
            22  O1a O    15.6302  -12.4435
            23  C1c C    39.8134  -13.6445
            24  C1c C    41.0030  -13.0147
            25  C1c C    38.6239  -12.9448
            26  C1b C    37.3642  -13.6445
            27  O1a O    36.1746  -12.9448
            28  O1a O    38.6239  -11.5452
            29  C1c C    42.1926  -13.6445
            30  C6a C    43.4522  -12.9448
            31  O6a O    44.6419  -13.6445
            32  O6a O    43.4522  -11.5452
            33  C1y C    38.6239  -15.8138
            34  O2x O    37.4342  -15.1141
            35  C1y C    38.6239  -17.1433
            36  C1y C    36.2446  -15.8138
            37  C1y C    37.4342  -17.8431
            38  O1a O    39.8834  -17.8431
            39  C1y C    36.2446  -17.1433
            40  C1b C    34.9851  -15.1141
            41  O1a O    37.4342  -19.2426
            42  O1a O    34.9851  -17.8431
            43  O1a O    33.7954  -15.8138
            44  O2a O    39.8134  -15.1141
            45  O1a O    41.0030  -11.5452
            46  O1a O    42.1926  -15.1141
BOND        47
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     5   9 1
            9     7  10 1
            10    8  11 1
            11   10  12 1
            12   12  13 1
            13   12  14 1 #Up
            14   13  15 1
            15   15  16 1
            16   16  17 2
            17   16  18 1
            18   17  19 1
            19   18  20 2
            20   19  21 2
            21   21  22 1
            22    6   8 1
            23   20  21 1
            24   23  24 1
            25   23  25 1
            26   25  26 1
            27   26  27 1
            28   25  28 1 #Up
            29   24  29 1
            30   29  30 1
            31   30  31 1
            32   30  32 2
            33   33  34 1
            34   33  35 1
            35   34  36 1
            36   35  37 1
            37   35  38 1 #Down
            38   36  39 1
            39   36  40 1 #Up
            40   37  41 1 #Up
            41   39  42 1 #Up
            42   40  43 1
            43   37  39 1
            44   33  44 1 #Up
            45   23  44 1 #Down
            46   24  45 1 #Down
            47   29  46 1 #Down

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