KEGG   DRUG: D04708Help
Entry
D04708                      Drug                                   

Name
Levdobutamine lactobionate (USAN)
Formula
C12H22O12. C18H23NO3
Exact mass
659.2789
Mol weight
659.676
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Cardiotonic
Comment
The target of Levdobutamine is beta1-adrenargic receptor.
Target
beta1-adrenergic receptor agonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor [HSA:153] [KO:K04141]
     Levdobutamine
      D04708  Levdobutamine lactobionate (USAN)
BRITE hierarchy
Other DBs
CAS: 
129388-07-4
PubChem: 
LigandBox: 
KCF data Show

ATOM        46
            1   C8y C    27.7415  -15.2344
            2   C8x C    28.9566  -14.5425
            3   C8x C    27.7358  -16.6357
            4   C1b C    26.5321  -14.5366
            5   C8y C    30.2361  -15.2460
            6   C8x C    28.9449  -17.3392
            7   C1b C    25.3169  -15.2344
            8   C8y C    30.2301  -16.6415
            9   O1a O    31.3813  -14.5542
            10  N1b N    24.1076  -14.5425
            11  O1a O    31.4395  -17.3449
            12  C1c C    22.9040  -15.2403
            13  C1b C    21.6888  -14.5425
            14  C1a C    22.9040  -16.6357
            15  C1b C    20.4793  -15.2403
            16  C8y C    19.2642  -14.5425
            17  C8x C    18.0607  -15.2403
            18  C8x C    19.2642  -13.1471
            19  C8x C    16.8454  -14.5425
            20  C8x C    18.0607  -12.4435
            21  C8y C    16.8454  -13.1471
            22  O1a O    15.6302  -12.4435
            23  C1c C    39.8134  -13.6445
            24  C1c C    41.0030  -13.0147
            25  C1c C    38.6239  -12.9448
            26  C1b C    37.3642  -13.6445
            27  O1a O    36.1746  -12.9448
            28  O1a O    38.6239  -11.5452
            29  C1c C    42.1926  -13.6445
            30  C6a C    43.4522  -12.9448
            31  O6a O    44.6419  -13.6445
            32  O6a O    43.4522  -11.5452
            33  C1y C    38.6239  -15.8138
            34  O2x O    37.4342  -15.1141
            35  C1y C    38.6239  -17.1433
            36  C1y C    36.2446  -15.8138
            37  C1y C    37.4342  -17.8431
            38  O1a O    39.8834  -17.8431
            39  C1y C    36.2446  -17.1433
            40  C1b C    34.9851  -15.1141
            41  O1a O    37.4342  -19.2426
            42  O1a O    34.9851  -17.8431
            43  O1a O    33.7954  -15.8138
            44  O2a O    39.8134  -15.1141
            45  O1a O    41.0030  -11.5452
            46  O1a O    42.1926  -15.1141
BOND        47
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     5   9 1
            9     7  10 1
            10    8  11 1
            11   10  12 1
            12   12  13 1
            13   12  14 1 #Up
            14   13  15 1
            15   15  16 1
            16   16  17 2
            17   16  18 1
            18   17  19 1
            19   18  20 2
            20   19  21 2
            21   21  22 1
            22    6   8 1
            23   20  21 1
            24   23  24 1
            25   23  25 1
            26   25  26 1
            27   26  27 1
            28   25  28 1 #Up
            29   24  29 1
            30   29  30 1
            31   30  31 1
            32   30  32 2
            33   33  34 1
            34   33  35 1
            35   34  36 1
            36   35  37 1
            37   35  38 1 #Down
            38   36  39 1
            39   36  40 1 #Up
            40   37  41 1 #Up
            41   39  42 1 #Up
            42   40  43 1
            43   37  39 1
            44   33  44 1 #Up
            45   23  44 1 #Down
            46   24  45 1 #Down
            47   29  46 1 #Down

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