KEGG   DRUG: D04728Help
Entry
D04728                      Drug                                   

Name
Licostinel (USAN/INN)
Formula
C8H3Cl2N3O4
Exact mass
274.9501
Mol weight
276.0331
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
NMDA antagonist
Remark
Drug group: 
Target
N-methyl-D-aspartate receptor antagonist [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04720  Long-term potentiation
hsa04724  Glutamatergic synapse  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Licostinel
      D04728  Licostinel (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
153504-81-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        17
            1   C8y C    14.1400  -17.6400
            2   C8y C    14.1400  -19.0400
            3   C8x C    15.3524  -19.7400
            4   C8y C    16.5649  -19.0400
            5   C8y C    16.5649  -17.6400
            6   C8y C    15.3524  -16.9400
            7   N4x N    17.7773  -19.7400
            8   C8y C    18.9897  -19.0400
            9   C8y C    18.9897  -17.6400
            10  N4x N    17.7773  -16.9400
            11  O5x O    20.1873  -16.9485
            12  O5x O    20.1873  -19.7315
            13  N2b N    15.3524  -15.5402 #+
            14  X   Cl   12.9276  -16.9400
            15  X   Cl   12.9276  -19.7400
            16  O3a O    14.1232  -14.8304
            17  O3a O    16.8280  -14.4298 #-
BOND        18
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 2
            13    8  12 2
            14    6  13 1
            15    1  14 1
            16    2  15 1
            17   13  16 2
            18   13  17 1

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