KEGG   DRUG: Lixazinone sulfateHelp
Entry
D04751                      Drug                                   

Name
Lixazinone sulfate (USAN)
Formula
C21H28N4O3. H2SO4. H2O
Exact mass
500.1941
Mol weight
500.5658
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01507  Phosphodiesterase III inhibitor
Activity
Cardiotonic [phosphodiesterase inhibitor]
Target
phosphodiesterase III [HSA:5139 5140] [KO:K19021 K13296]
  Pathway
Purine metabolism
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   phosphodiesterase (PDE) III
    Lixazinone
     D04751  Lixazinone sulfate (USAN)
BRITE hierarchy
Other DBs
CAS: 
101626-67-9
PubChem: 
LigandBox: 
KCF data Show

ATOM        34
            1   C8x C    12.5300   -3.6400
            2   C8y C    12.5300   -5.0400
            3   C8x C    13.7424   -5.7400
            4   C8y C    14.9549   -5.0400
            5   C8y C    14.9549   -3.6400
            6   C8x C    13.7424   -2.9400
            7   C1x C    16.1673   -5.7400
            8   N1y N    17.3797   -5.0400
            9   C2y C    17.3797   -3.6400
            10  N2x N    16.1673   -2.9400
            11  C1x C    18.7112   -5.4726
            12  C5x C    19.5341   -4.3400
            13  N1x N    18.7112   -3.2074
            14  O5x O    20.9300   -4.3400
            15  O2a O    11.3176   -5.7400
            16  C1b C    10.1221   -5.0496
            17  C1b C     8.9347   -5.7351
            18  C1b C     7.7435   -5.0471
            19  C5a C     6.5540   -5.7338
            20  N1c N     5.3639   -5.0465
            21  C1y C     4.1738   -5.7335
            22  O5a O     6.5538   -7.1398
            23  C1a C     5.3639   -3.6402
            24  C1x C     2.9840   -5.0463
            25  C1x C     1.7714   -5.7461
            26  C1x C     1.7712   -7.1461
            27  C1x C     2.9611   -7.8333
            28  C1x C     4.1736   -7.1335
            29  S4a S    12.5948   -9.4641
            30  O1d O    14.0046   -9.4641
            31  O1d O    11.1850   -9.4342
            32  O1d O    12.5880  -10.8739
            33  O1d O    12.5985   -8.0543
            34  O0  O    18.5801   -9.3886
BOND        35
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12    8  11 1
            13   11  12 1
            14   12  13 1
            15    9  13 1
            16   12  14 2
            17    2  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   19  22 2
            25   20  23 1
            26   21  24 1
            27   24  25 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   21  28 1
            32   29  30 1
            33   29  31 1
            34   29  32 2
            35   29  33 2

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