KEGG   DRUG: D04751Help
Entry
D04751                      Drug                                   

Name
Lixazinone sulfate (USAN)
Formula
C21H28N4O3. H2SO4. H2O
Exact mass
500.1941
Mol weight
500.5658
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Cardiotonic [phosphodiesterase inhibitor]
Target
phosphodiesterase III inhibitor [HSA:5139 5140] [KO:K13296]
  Pathway
hsa00230  Purine metabolism
hsa04910  Insulin signaling pathway
hsa04914  Progesterone-mediated oocyte maturation  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   phosphodiesterase (PDE) III
    Lixazinone
     D04751  Lixazinone sulfate (USAN)
BRITE hierarchy
Other DBs
CAS: 
101626-67-9
PubChem: 
LigandBox: 
KCF data Show

ATOM        34
            1   C8x C    12.5300   -3.6400
            2   C8y C    12.5300   -5.0400
            3   C8x C    13.7424   -5.7400
            4   C8y C    14.9549   -5.0400
            5   C8y C    14.9549   -3.6400
            6   C8x C    13.7424   -2.9400
            7   C1x C    16.1673   -5.7400
            8   N1y N    17.3797   -5.0400
            9   C2y C    17.3797   -3.6400
            10  N2x N    16.1673   -2.9400
            11  C1x C    18.7112   -5.4726
            12  C5x C    19.5341   -4.3400
            13  N1x N    18.7112   -3.2074
            14  O5x O    20.9300   -4.3400
            15  O2a O    11.3176   -5.7400
            16  C1b C    10.1221   -5.0496
            17  C1b C     8.9347   -5.7351
            18  C1b C     7.7435   -5.0471
            19  C5a C     6.5540   -5.7338
            20  N1c N     5.3639   -5.0465
            21  C1y C     4.1738   -5.7335
            22  O5a O     6.5538   -7.1398
            23  C1a C     5.3639   -3.6402
            24  C1x C     2.9840   -5.0463
            25  C1x C     1.7714   -5.7461
            26  C1x C     1.7712   -7.1461
            27  C1x C     2.9611   -7.8333
            28  C1x C     4.1736   -7.1335
            29  S4a S    12.5948   -9.4641
            30  O1d O    14.0046   -9.4641
            31  O1d O    11.1850   -9.4342
            32  O1d O    12.5880  -10.8739
            33  O1d O    12.5985   -8.0543
            34  O0  O    18.5801   -9.3886
BOND        35
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12    8  11 1
            13   11  12 1
            14   12  13 1
            15    9  13 1
            16   12  14 2
            17    2  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   19  22 2
            25   20  23 1
            26   21  24 1
            27   24  25 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   21  28 1
            32   29  30 1
            33   29  31 1
            34   29  32 2
            35   29  33 2

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