KEGG   DRUG: D04785Help
Entry
D04785                      Drug                                   

Name
Lotrafiban hydrochloride (USAN)
Formula
C23H32N4O4. HCl
Exact mass
464.219
Mol weight
464.9855
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antithrombotic;
Platelet aggregation inhibitor
Target
glycoprotein alphaIIb/beta3 (GPIIb/IIIa) receptor antagonist [HSA:3674 3690] [KO:K06476 K06493]
  Pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction  
 
Brite
Target-based classification of drugs [BR:br08310]
 Others
  Cell adhesion molecules (CAMs)
   glycoprotein alpha IIb/beta3 (GPIIb/IIIa) receptor [HSA:3674 3690] [KO:K06476 K06493]
    Lotrafiban
     D04785  Lotrafiban hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
179599-82-7
PubChem: 
LigandBox: 
KCF data Show

ATOM        32
            1   C8y C    32.4265  -17.6314
            2   N1x N    33.6829  -16.9334
            3   C1y C    34.9392  -17.4918
            4   C5x C    35.2882  -18.8877
            5   C8y C    32.1473  -18.9575
            6   N1y N    34.4506  -20.0045
            7   C1x C    33.0547  -20.0045
            8   C8x C    31.3796  -16.7240
            9   C8x C    30.0534  -17.1428
            10  C8y C    29.7742  -18.5388
            11  C8x C    30.8212  -19.4461
            12  C1a C    35.1486  -21.2608
            13  O5x O    36.6841  -19.0971
            14  C1b C    35.9861  -16.5844
            15  C6a C    37.3123  -17.0730
            16  O6a O    38.3592  -16.1657
            17  O6a O    37.5915  -18.4690
            18  C5a C    28.5642  -19.2430
            19  N1y N    27.3184  -18.5357
            20  O5a O    28.5741  -20.6310
            21  C1x C    27.3184  -17.1357
            22  C1x C    26.1060  -16.4357
            23  C1y C    24.8935  -17.1357
            24  C1x C    24.8935  -18.5357
            25  C1x C    26.1060  -19.2357
            26  C1y C    23.7071  -16.4507
            27  C1x C    23.7072  -15.0502
            28  C1x C    22.4947  -14.3502
            29  N1x N    21.2823  -15.0502
            30  C1x C    21.2823  -16.4507
            31  C1x C    22.4947  -17.1507
            32  X   Cl   39.7479  -20.0092
BOND        34
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     1   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    5  11 2
            13    6  12 1
            14    4  13 2
            15    3  14 1 #Up
            16   14  15 1
            17   15  16 1
            18   15  17 2
            19   10  18 1
            20   18  19 1
            21   18  20 2
            22   19  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   19  25 1
            28   23  26 1
            29   26  27 1
            30   27  28 1
            31   28  29 1
            32   29  30 1
            33   30  31 1
            34   26  31 1

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